[Term]
id: PR:000062835
name: DNA-directed RNA polymerase II subunit RPB1 phosphorylated and ubiquitinated 1 (human)
def: "A DNA-directed RNA polymerase II subunit RPB1 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-1843, Ser-1847, Ser-1850, Ser-1857, Ser-1861, Ser-1864, Ser-1868, Ser-1871, Ser-1875, Ser-1878, Ser-1882, Ser-1889, Ser-1892, Ser-1896, Ser-1899, Ser-1906, Ser-1910, Ser-1913, Ser-1917, Ser-1920, Ser-1924, Ser-1927, Ser-1931, and Ser-1934 of the amino acid sequence represented by UniProtKB:P24928-1 and that includes at least 1 ubiquitinated lysine. Example: UniProtKB:P24928-1, Ser-1843/Ser-1847/Ser-1850/Ser-1857/Ser-1861/Ser-1864/Ser-1868/Ser-1871/Ser-1875/Ser-1878/Ser-1882/Ser-1889/Ser-1892/Ser-1896/Ser-1899/Ser-1906/Ser-1910/Ser-1913/Ser-1917/Ser-1920/Ser-1924/Ser-1927/Ser-1931/Ser-1934, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-6781855]
comment: Category=organism-modification.
synonym: "hPOLR2A/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ub,p-S2,S5(CTD)-POLR2A" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-6781855]
synonym: "UniProtKB:P24928, Ser-1843/Ser-1847/Ser-1850/Ser-1857/Ser-1861/Ser-1864/Ser-1868/Ser-1871/Ser-1875/Ser-1878/Ser-1882/Ser-1889/Ser-1892/Ser-1896/Ser-1899/Ser-1906/Ser-1910/Ser-1913/Ser-1917/Ser-1920/Ser-1924/Ser-1927/Ser-1931/Ser-1934, MOD:00046|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P24928-1, Ser-1843/Ser-1847/Ser-1850/Ser-1857/Ser-1861/Ser-1864/Ser-1868/Ser-1871/Ser-1875/Ser-1878/Ser-1882/Ser-1889/Ser-1892/Ser-1896/Ser-1899/Ser-1906/Ser-1910/Ser-1913/Ser-1917/Ser-1920/Ser-1924/Ser-1927/Ser-1931/Ser-1934, MOD:00046|MOD:01148" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6781855 "PR:000062835 located_in GO:0005654"
is_a: PR:P24928 ! DNA-directed RNA polymerase II subunit RPB1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens