[Term]
id: PR:000063066
name: fibroblast growth factor receptor 2 isoform h3 sequence variant P253R, signal peptide removed phosphorylated 1 (human)
def: "A fibroblast growth factor receptor 2 isoform h3 (human) that has an Arg residue at the position equivalent to Pro-253 of the amino acid sequence represented by UniProtKB:P21802-3, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-467, Tyr-587, Tyr-589, Tyr-657, Tyr-658, Tyr-734, Tyr-770, and Tyr-780. UniProtKB:P21802-3, 22-822, Pro-253, CHEBI:29952|Tyr-467/Tyr-587/Tyr-589/Tyr-657/Tyr-658/Tyr-734/Tyr-770/Tyr-780, MOD:00048." [PRO:DNx, Reactome:R-HSA-2011877]
comment: Category=organism-modification.
synonym: "hFGFR2/iso:h3/var:P253R/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-8Y-FGFR2b P253R" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2011877]
synonym: "UniProtKB:P21802-3, 22-822, Pro-253, CHEBI:29952|Tyr-467/Tyr-587/Tyr-589/Tyr-657/Tyr-658/Tyr-734/Tyr-770/Tyr-780, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2011877 "PR:000063066 located_in GO:0005886"
is_a: PR:P21802-3 ! fibroblast growth factor receptor 2 isoform h3 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens