[Term]
id: PR:000063201
name: fibroblast growth factor receptor 2 sequence variant T660M, signal peptide removed phosphotyrosine (human)
def: "A fibroblast growth factor receptor 2 (human) that has a Met residue at the position equivalent to Thr-660 of the amino acid sequence represented by UniProtKB:P21802-1, that has had the signal peptide removed, and that includes at least 8 phosphorylated tyrosines. Example: UniProtKB:P21802-1, 22-821, Thr-660, CHEBI:16044|MOD:00048(8+)." [PRO:DNx, Reactome:R-HSA-2033300]
comment: Category=organism-modification.
synonym: "hFGFR2/var:T660M/SigPep-/PhosTyr(8+)" EXACT PRO-short-label [PRO:DNx]
synonym: "p-8Y-FGFR2 K660M" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2033300]
synonym: "UniProtKB:P21802, 22-821, Thr-660, CHEBI:16044|MOD:00048(8+)" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P21802-1, 22-821, Thr-660, CHEBI:16044|MOD:00048(8+)" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2033300 "PR:000063201 located_in GO:0005886"
is_a: PR:P21802 ! fibroblast growth factor receptor 2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens