[Term]
id: PR:000063247
name: fibroblast growth factor receptor 3 sequence variant K650E, signal peptide removed phosphotyrosine (human)
def: "A fibroblast growth factor receptor 3 (human) that has a Glu residue at the position equivalent to Lys-650 of the amino acid sequence represented by UniProtKB:P22607-1, that has had the signal peptide removed, and that includes at least 6 phosphorylated tyrosines. Example: UniProtKB:P22607-1, 23-806, Lys-650, CHEBI:29972|MOD:00048(6+)." [PRO:DNx, Reactome:R-HSA-2032952]
comment: Category=organism-modification.
synonym: "hFGFR3/var:K650E/SigPep-/PhosTyr(6+)" EXACT PRO-short-label [PRO:DNx]
synonym: "p-6Y-FGFR3 K650E" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2032952]
synonym: "UniProtKB:P22607, 23-806, Lys-650, CHEBI:29972|MOD:00048(6+)" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P22607-1, 23-806, Lys-650, CHEBI:29972|MOD:00048(6+)" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2032952 "PR:000063247 located_in GO:0005886"
is_a: PR:P22607 ! fibroblast growth factor receptor 3 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens