[Term]
id: PR:000063333
name: signal transducer and activator of transcription 3 acetylated and phosphorylated 1 (human)
def: "A signal transducer and activator of transcription 3 (human) that has been acetylated on the residue at the position equivalent to Lys-685 and phosphorylated on the residues at the positions equivalent to Tyr-705 and Ser-727 of the amino acid sequence represented by UniProtKB:P40763-1. Example: UniProtKB:P40763-1, Lys-685, MOD:00064|Tyr-705, MOD:00048|Ser-727, MOD:00046." [PRO:DNx, Reactome:R-HSA-9701435]
comment: Category=organism-modification.
synonym: "hSTAT3/AcPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "AcK685- p-Y705,S727-STAT3" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9701435]
synonym: "UniProtKB:P40763, Lys-685, MOD:00064|Tyr-705, MOD:00048|Ser-727, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40763-1, Lys-685, MOD:00064|Tyr-705, MOD:00048|Ser-727, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9701435 "PR:000063333 located_in GO:0005654"
is_a: PR:P40763 ! signal transducer and activator of transcription 3 (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens