[Term]
id: PR:000063546
name: dual specificity mitogen-activated protein kinase kinase 1 sequence variant F53L, initiator methionine removed form (human)
def: "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Leu residue at the position equivalent to Phe-53 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Phe-53, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-9652031]
comment: Category=organism-modification.
synonym: "hMAP2K1/var:F53L/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "MAP2K1 F53L" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9652031]
synonym: "UniProtKB:Q02750, 2-393, Phe-53, CHEBI:30006" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q02750-1, 2-393, Phe-53, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9652031 "PR:000063546 located_in GO:0005829"
is_a: PR:Q02750 ! dual specificity mitogen-activated protein kinase kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens