[Term]
id: PR:000063639
name: mothers against decapentaplegic homolog 3 sequence variant D258N phosphorylated 1 (human)
def: "A mothers against decapentaplegic homolog 3 (human) that has an Asn residue at the position equivalent to Asp-258 of the amino acid sequence represented by UniProtKB:P84022-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-423 and Ser-425. Example: UniProtKB:P84022-1, Asp-258, CHEBI:50347|Ser-423/Ser-425, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315470]
comment: Category=organism-modification.
synonym: "hSMAD3/var:D258N/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-S423,S425-SMAD3 D258N" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-3315470]
synonym: "UniProtKB:P84022, Asp-258, CHEBI:50347|Ser-423/Ser-425, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P84022-1, Asp-258, CHEBI:50347|Ser-423/Ser-425, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3315470 "PR:000063639 located_in GO:0005829"
is_a: PR:P84022 ! mothers against decapentaplegic homolog 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens