[Term]
id: PR:000063683
name: serine/threonine-protein kinase/endoribonuclease IRE1, signal peptide removed phosphorylated 1 (human)
def: "A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Ser-724 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, 19-977, Ser-724, MOD:00046." [PRO:DNx, Reactome:R-HSA-381029]
comment: Category=organism-modification.
synonym: "hERN1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-S724-ERN1" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-381029]
synonym: "UniProtKB:O75460, 19-977, Ser-724, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:O75460-1, 19-977, Ser-724, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-381029 "PR:000063683 located_in GO:0005789"
is_a: PR:O75460 ! serine/threonine-protein kinase/endoribonuclease IRE1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens