[Term]
id: PR:000064151
name: fibroblast growth factor receptor 1 sequence variant R576W, signal peptide removed phosphorylated 1 (human)
def: "A fibroblast growth factor receptor 1 (human) that has a Trp residue at the position equivalent to Arg-576 of the amino acid sequence represented by UniProtKB:P11362-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-463, Tyr-583, Tyr-585, Tyr-653, Tyr-654, Tyr-730, Tyr-766, and Tyr-776. Example: UniProtKB:P11362-1, 22-822, Tyr-463/Tyr-583/Tyr-585/Tyr-653/Tyr-654/Tyr-730/Tyr-766/Tyr-776, MOD:00048|Arg-576, CHEBI:29954." [PRO:DNx, Reactome:R-HSA-2023361]
comment: Category=organism-modification.
synonym: "hFGFR1/var:R576W/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-8Y- FGFR1 R576W" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2023361]
synonym: "UniProtKB:P11362, 22-822, Tyr-463/Tyr-583/Tyr-585/Tyr-653/Tyr-654/Tyr-730/Tyr-766/Tyr-776, MOD:00048|Arg-576, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P11362-1, 22-822, Tyr-463/Tyr-583/Tyr-585/Tyr-653/Tyr-654/Tyr-730/Tyr-766/Tyr-776, MOD:00048|Arg-576, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2023361 "PR:000064151 located_in GO:0005886"
is_a: PR:P11362 ! fibroblast growth factor receptor 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens