[Term]
id: PR:000064466
name: epidermal growth factor receptor sequence variant L858R, signal peptide removed form (human)
def: "An epidermal growth factor receptor (human) that has an Arg residue at the position equivalent to Leu-858 of the amino acid sequence represented by UniProtKB:P00533-1 and that has had the signal peptide removed. Example: UniProtKB:P00533-1, 25-1210, Leu-858, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-1173212]
comment: Category=organism-modification.
synonym: "hEGFR/var:L858R/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "EGFR L858R" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1173212]
synonym: "UniProtKB:P00533, 25-1210, Leu-858, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210, Leu-858, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1173212 "PR:000064466 located_in GO:0005886"
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens