[Term]
id: PR:000064476
name: ALK tyrosine kinase receptor sequence variant G881D, signal peptide removed form (human)
def: "An ALK tyrosine kinase receptor (human) that has an Asp residue at the position equivalent to Gly-881 of the amino acid sequence represented by UniProtKB:Q9UM73 and that has had the signal peptide removed. UniProtKB:Q9UM73, 19-1620, Gly-881, CHEBI:29958." [PRO:DNx, Reactome:R-HSA-9715260]
comment: Category=organism-modification.
synonym: "hALK/var:G881D/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "ALK G881D" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9715260]
synonym: "UniProtKB:Q9UM73, 19-1620, Gly-881, CHEBI:29958" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9715260 "PR:000064476 located_in GO:0005886"
is_a: PR:Q9UM73 ! ALK tyrosine kinase receptor (human)
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens