[Term]
id: PR:000064560
name: sonic hedgehog protein sequence variant H374R, signal peptide removed ubiquitinated form (human)
def: "A sonic hedgehog protein (human) that has an Arg residue at the position equivalent to His-374 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, His-374, CHEBI:29952|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387352, Reactome:R-HSA-5387360]
comment: Category=organism-modification.
synonym: "hSHH/var:H374R/SigPep-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "ub-SHH(24-462) H374R" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-5387352, Reactome:R-HSA-5387360]
synonym: "UniProtKB:Q15465, 24-462, His-374, CHEBI:29952|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5387352 "PR:000064560 located_in GO:0005788"
xref: Reactome:R-HSA-5387360 "PR:000064560 located_in GO:0005829"
is_a: PR:Q15465 ! sonic hedgehog protein (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens