[Term]
id: PR:000064628
name: transcriptional activator GLI3 phosphorylated and ubiquitinated 1 (human)
def: "A transcriptional activator GLI3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-849, Ser-865, Ser-877, Ser-907, Ser-980 and Ser-1006, and ubiquitinated on the residues at the positions equivalent to Lys-773, Lys-779, Lys-784, and Lys-800 of the amino acid sequence represented by UniProtKB:P10071 and that includes at least 7 additional phosphorylated serines. UniProtKB:P10071, Lys-773/Lys-779/Lys-784/Lys-800, MOD:01148|Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(7+)." [PRO:DNx, Reactome:R-HSA-5610506]
comment: Category=organism-modification.
synonym: "hGLI3/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "ub-p13S-GLI3" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-5610506]
synonym: "UniProtKB:P10071, Lys-773/Lys-779/Lys-784/Lys-800, MOD:01148|Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(7+)" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5610506 "PR:000064628 located_in GO:0097546"
is_a: PR:P10071 ! transcriptional activator GLI3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens