[Term]
id: PR:000064646
name: macrophage colony-stimulating factor 1 receptor, signal peptide removed phosphorylated and ubiquitinated 1 (human)
def: "A macrophage colony-stimulating factor 1 receptor (human) that has had the signal peptide removed, that has been phosphorylated on the residues at the positions equivalent to Tyr-546, Tyr-561, Tyr-699, Tyr-708, Tyr-723, Tyr-809, Tyr-923, and Tyr-969 of the amino acid sequence represented by UniProtKB:P07333-1, and that includes at least 1 ubiquitinated lysine. Example: UniProtKB:P07333-1, 20-972, Tyr-546/Tyr-561/Tyr-699/Tyr-708/Tyr-723/Tyr-809/Tyr-923/Tyr-969, MOD:00048|MOD:01148." [PRO:DNx, Reactome:R-HSA-389142]
comment: Category=organism-modification.
synonym: "hCSF1R/SigPep-/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PolyUb,p-8Y-CSF1R" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-389142]
synonym: "UniProtKB:P07333, 20-972, Tyr-546/Tyr-561/Tyr-699/Tyr-708/Tyr-723/Tyr-809/Tyr-923/Tyr-969, MOD:00048|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P07333-1, 20-972, Tyr-546/Tyr-561/Tyr-699/Tyr-708/Tyr-723/Tyr-809/Tyr-923/Tyr-969, MOD:00048|MOD:01148" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-389142 "PR:000064646 located_in GO:0005886"
is_a: PR:P07333 ! macrophage colony-stimulating factor 1 receptor (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens