[Term]
id: PR:000064752
name: hepatocyte growth factor receptor, signal peptide removed phosphorylated and ubiquitinated 1 (human)
def: "A hepatocyte growth factor receptor (human) that has had the signal peptide removed, that has been phosphorylated on the residues at the positions equivalent to Tyr-1234, Tyr-1235, Tyr-1349, and Tyr-1356 of the amino acid sequence represented by UniProtKB:P08581-1, and that includes at least 1 ubiquitinated lysine. Example: UniProtKB:P08581-1, 25-1390, Tyr-1234/Tyr-1235/Tyr-1349/Tyr-1356, MOD:00048|MOD:01148." [PRO:DNx, Reactome:R-HSA-8875181]
comment: Category=organism-modification.
synonym: "hMET/SigPep-/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-8875181]
synonym: "UniProtKB:P08581, 25-1390, Tyr-1234/Tyr-1235/Tyr-1349/Tyr-1356, MOD:00048|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P08581-1, 25-1390, Tyr-1234/Tyr-1235/Tyr-1349/Tyr-1356, MOD:00048|MOD:01148" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8875181 "PR:000064752 located_in GO:0005886"
is_a: PR:P08581 ! hepatocyte growth factor receptor (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens