[Term]
id: PR:000064767
name: mitogen-activated protein kinase kinase kinase 7 phosphorylated and ubiquitinated 1 (human)
def: "A mitogen-activated protein kinase kinase kinase 7 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-178, Thr-184, Thr-187 and Ser-192, and ubiquitinated on the residues at the positions equivalent to Lys-34 and Lys-158 of the amino acid sequence represented by UniProtKB:O43318-1. Example: UniProtKB:O43318-1, Lys-34/Lys-158, MOD:01148|Thr-178/Thr-184/Thr-187, MOD:00047|Ser-192, MOD:00046." [PRO:DNx, Reactome:R-HSA-5607649]
comment: Category=organism-modification.
synonym: "hMAP3K7/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "K63polyUb-34,158-p-T178,184,187,S192-TAK1" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-5607649]
synonym: "UniProtKB:O43318, Lys-34/Lys-158, MOD:01148|Thr-178/Thr-184/Thr-187, MOD:00047|Ser-192, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:O43318-1, Lys-34/Lys-158, MOD:01148|Thr-178/Thr-184/Thr-187, MOD:00047|Ser-192, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5607649 "PR:000064767 located_in GO:0005829"
is_a: PR:O43318 ! mitogen-activated protein kinase kinase kinase 7 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens