[Term]
id: PR:000064810
name: proinsulin isoform 1 (human)
def: "A preproinsulin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01308-1 and that has had the signal peptide removed. UniProtKB:P01308-1, 25-110." [PRO:DAN, UniProtKB:P01308]
comment: Category=organism-modification. Requested by=MAxO.
synonym: "hINS/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "INS(25-110)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-264893]
synonym: "insulin isoform 1, signal peptide removed form (human)" EXACT [PRO:DNx]
synonym: "UniProtKB:P01308-1, 25-110" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-264893 "PR:000086054 located_in GO:0005788"
is_a: PR:P01308 ! preproinsulin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens