[Term]
id: PR:000064823
name: E3 ubiquitin-protein ligase CBL phosphorylated and ubiquitinated 1 (human)
def: "An E3 ubiquitin-protein ligase CBL (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-700, Tyr-731, and Tyr-774 of the amino acid sequence represented by UniProtKB:P22681 and that includes at least 1 ubiquitinated lysine. UniProtKB:P22681, Tyr-700/Tyr-731/Tyr-774, MOD:00048|MOD:01148." [PRO:DNx, Reactome:R-HSA-8848826]
comment: Category=organism-modification.
synonym: "hCBL/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PolyUb,p-Y700,Y731,Y774-CBL" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-8848826]
synonym: "UniProtKB:P22681, Tyr-700/Tyr-731/Tyr-774, MOD:00048|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8848826 "PR:000064823 located_in GO:0005829"
is_a: PR:P22681 ! E3 ubiquitin-protein ligase CBL (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens