[Term]
id: PR:000064859
name: mothers against decapentaplegic homolog 3 phosphorylated and ubiquitinated 1 (human)
def: "A mothers against decapentaplegic homolog 3 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-179, Ser-423, and Ser-425 of the amino acid sequence represented by UniProtKB:P84022-1 and that includes at least 1 ubiquitinated lysine. Example: UniProtKB:P84022-1, Thr-179, MOD:00047|Ser-423/Ser-425, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-9773841]
comment: Category=organism-modification.
synonym: "hSMAD3/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ub,p-T179,S423,S425-SMAD3" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9773841]
synonym: "UniProtKB:P84022, Thr-179, MOD:00047|Ser-423/Ser-425, MOD:00046|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P84022-1, Thr-179, MOD:00047|Ser-423/Ser-425, MOD:00046|MOD:01148" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9773841 "PR:000064859 located_in GO:0005654"
is_a: PR:P84022 ! mothers against decapentaplegic homolog 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens