[Term]
id: PR:000077147
name: beta-secretase 1, mature acetylated 1 (human)
def: "A beta-secretase 1 (human) that has had the signal peptide and propeptide removed, and that has been acetylated on the residues at the positions equivalent to Lys-126, Lys-275, Lys-279, Lys-285, Lys-299, Lys-300, and Lys-307 of the amino acid sequence represented by UniProtKB:P56817-1. Example: UniProtKB:P56817-1, 46-501, Lys-126/Lys-275/Lys-279/Lys-285/Lys-299/Lys-300/Lys-307, MOD:00064." [PRO:DNx, Reactome:R-HSA-5693106]
comment: Category=organism-modification.
synonym: "hBACE1/mature/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P56817, 46-501, Lys-126/Lys-275/Lys-279/Lys-285/Lys-299/Lys-300/Lys-307, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P56817-1, 46-501, Lys-126/Lys-275/Lys-279/Lys-285/Lys-299/Lys-300/Lys-307, MOD:00064" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "7K-BACE1(46-501)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-5693106]
xref: Reactome:R-HSA-5693106 "PR:000077147 located_in GO:0070931"
is_a: PR:P56817 ! beta-secretase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: lacks_part SO:0001062 ! propeptide