[Term]
id: PR:000085801
name: neurogenic locus notch homolog protein 2, signal peptide removed O-glycosylated 2 (human)
def: "A neurogenic locus notch homolog protein 2 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Thr-78, Thr-120, Ser-150, Thr-158, Thr-197, Thr-235, Thr-314, Thr-352, Ser-381, Ser-462, Thr-470, Ser-500, Ser-538, Ser-613, Ser-651, Ser-688, Thr-696, Ser-726, Ser-763, Thr-771, Ser-801, Thr-809, Ser-879, Ser-925, Ser-955, Thr-963, Thr-1001, Ser-1031, Thr-1039, Thr-1077, Ser-1155, Thr-1163, Thr-1201, Ser-1270, and Thr-1318 of the amino acid sequence represented by UniProtKB:Q04721. UniProtKB:Q04721, 26-2471, Thr-78/Thr-120/Thr-158/Thr-197/Thr-235/Thr-314/Thr-352/Thr-470/Thr-696/Thr-771/Thr-809/Thr-963/Thr-1001/Thr-1039/Thr-1077/Thr-1163/Thr-1201/Thr-1318, MOD:00813|Ser-150/Ser-381/Ser-462/Ser-500/Ser-538/Ser-613/Ser-651/Ser-688/Ser-726/Ser-763/Ser-801/Ser-879/Ser-955/Ser-1031/Ser-1155/Ser-1270, MOD:00804|Ser-925, MOD:00812." [PRO:DNx, Reactome:R-HSA-1467379, Reactome:R-HSA-1472874]
comment: Category=organism-modification.
synonym: "hNOTCH2/SigPep-/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "18xFucT-16xGlcS-FucS-NOTCH2(26-2471)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1467379, Reactome:R-HSA-1472874]
synonym: "UniProtKB:Q04721, 26-2471, Thr-78/Thr-120/Thr-158/Thr-197/Thr-235/Thr-314/Thr-352/Thr-470/Thr-696/Thr-771/Thr-809/Thr-963/Thr-1001/Thr-1039/Thr-1077/Thr-1163/Thr-1201/Thr-1318, MOD:00813|Ser-150/Ser-381/Ser-462/Ser-500/Ser-538/Ser-613/Ser-651/Ser-688/Ser-726/Ser-763/Ser-801/Ser-879/Ser-955/Ser-1031/Ser-1155/Ser-1270, MOD:00804|Ser-925, MOD:00812" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1467379 "PR:000085801 located_in GO:0005789"
xref: Reactome:R-HSA-1472874 "PR:000085801 located_in GO:0000139"
is_a: PR:Q04721 ! neurogenic locus notch homolog protein 2 (human)
relationship: has_part MOD:00812 ! O-fucosyl-L-serine
relationship: has_part MOD:00813 ! O-fucosyl-L-threonine
relationship: has_part MOD:00804 ! O-glucosyl-L-serine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens