[Term]
id: PR:000085899
name: neurogenic locus notch homolog protein 1, signal peptide removed O-glycosylated 3 (human)
def: "A neurogenic locus notch homolog protein 1 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Thr-73, Thr-116, Ser-146, Thr-194, Thr-232, Thr-311, Thr-349, Ser-378, Ser-458, Thr-466, Ser-496, Ser-534, Ser-609, Thr-617, Ser-647, Thr-692, Ser-722, Ser-759, Thr-767, Ser-797, Thr-805, Ser-883, Ser-921, Thr-997, Ser-1027, Thr-1035, Ser-1065, Thr-1159, Ser-1189, Thr-1197, Thr-1243, Ser-1273, Thr-1321, Thr-1362, and Thr-1402 of the amino acid sequence represented by UniProtKB:P46531. UniProtKB:P46531, 19-2555, Thr-73/Thr-116/Thr-194/Thr-232/Thr-311/Thr-349/Thr-466/Thr-617/Thr-692/Thr-767/Thr-805/Thr-997/Thr-1035/Thr-1159/Thr-1197/Thr-1243/Thr-1321/Thr-1362/Thr-1402, MOD:00813|Ser-146/Ser-378/Ser-458/Ser-496/Ser-534/Ser-609/Ser-647/Ser-722/Ser-759/Ser-797/Ser-1027/Ser-1065/Ser-1189/Ser-1273, MOD:00804|Ser-883/Ser-921, MOD:00812." [PRO:DNx, Reactome:R-HSA-1467425]
comment: Category=organism-modification.
synonym: "hNOTCH1/SigPep-/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "19xFucT-14xGlcS-2xFucS-NOTCH1(19-2555)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1467425]
synonym: "UniProtKB:P46531, 19-2555, Thr-73/Thr-116/Thr-194/Thr-232/Thr-311/Thr-349/Thr-466/Thr-617/Thr-692/Thr-767/Thr-805/Thr-997/Thr-1035/Thr-1159/Thr-1197/Thr-1243/Thr-1321/Thr-1362/Thr-1402, MOD:00813|Ser-146/Ser-378/Ser-458/Ser-496/Ser-534/Ser-609/Ser-647/Ser-722/Ser-759/Ser-797/Ser-1027/Ser-1065/Ser-1189/Ser-1273, MOD:00804|Ser-883/Ser-921, MOD:00812" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1467425 "PR:000085899 located_in GO:0005789"
is_a: PR:P46531 ! neurogenic locus notch homolog protein 1 (human)
relationship: has_part MOD:00812 ! O-fucosyl-L-serine
relationship: has_part MOD:00813 ! O-fucosyl-L-threonine
relationship: has_part MOD:00804 ! O-glucosyl-L-serine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens