[Term]
id: PR:000085917
name: neurogenic locus notch homolog protein 3, signal peptide removed O-glycosylated 2 (human)
def: "A neurogenic locus notch homolog protein 3 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Ser-84, Ser-125, Thr-173, Thr-211, Thr-250, Thr-290, Thr-328, Ser-357, Ser-437, Thr-445, Ser-475, Ser-513, Ser-588, Ser-626, Ser-663, Ser-671, Ser-740, Thr-748, Ser-863, Ser-893, Thr-938, Ser-968, Thr-1098, Ser-1128, Ser-1136, Thr-1181, Ser-1252, and Ser-1349 of the amino acid sequence represented by UniProtKB:Q9UM47. UniProtKB:Q9UM47, 40-2321, Ser-84/Ser-125/Ser-357/Ser-437/Ser-475/Ser-513/Ser-588/Ser-626/Ser-663/Ser-740/Ser-893/Ser-968/Ser-1128/Ser-1252, MOD:00804|Thr-173/Thr-211/Thr-250/Thr-290/Thr-328/Thr-445/Thr-748/Thr-938/Thr-1098/Thr-1181, MOD:00813|Ser-671/Ser-863/Ser-1136/Ser-1349, MOD:00812." [PRO:DNx, Reactome:R-HSA-1467307, Reactome:R-HSA-1472871]
comment: Category=organism-modification.
synonym: "hNOTCH3/SigPep-/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1467307, Reactome:R-HSA-1472871]
synonym: "UniProtKB:Q9UM47, 40-2321, Ser-84/Ser-125/Ser-357/Ser-437/Ser-475/Ser-513/Ser-588/Ser-626/Ser-663/Ser-740/Ser-893/Ser-968/Ser-1128/Ser-1252, MOD:00804|Thr-173/Thr-211/Thr-250/Thr-290/Thr-328/Thr-445/Thr-748/Thr-938/Thr-1098/Thr-1181, MOD:00813|Ser-671/Ser-863/Ser-1136/Ser-1349, MOD:00812" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1467307 "PR:000085917 located_in GO:0005789"
xref: Reactome:R-HSA-1472871 "PR:000085917 located_in GO:0000139"
is_a: PR:Q9UM47 ! neurogenic locus notch homolog protein 3 (human)
relationship: has_part MOD:00812 ! O-fucosyl-L-serine
relationship: has_part MOD:00813 ! O-fucosyl-L-threonine
relationship: has_part MOD:00804 ! O-glucosyl-L-serine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens