[Term]
id: PR:000085921
name: neurogenic locus notch homolog protein 4, signal peptide removed O-glycosylated 2 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Thr-40, Ser-79, Ser-210, Thr-248, Thr-290, Thr-331, Thr-369, Ser-451, Ser-481, Thr-489, Ser-519, Ser-557, Ser-595, Ser-603, Ser-697, Thr-705, Ser-735, Ser-743, Thr-781, Thr-820, Thr-944, Ser-974, Thr-982, Ser-1052, Thr-1060, and Ser-1145 of the amino acid sequence represented by UniProtKB:Q99466-1. Example: UniProtKB:Q99466-1, 24-2003, Thr-40/Thr-248/Thr-290/Thr-331/Thr-369/Thr-489/Thr-705/Thr-781/Thr-820/Thr-944/Thr-982/Thr-1060, MOD:00813|Ser-79/Ser-210/Ser-451/Ser-603/Ser-743/Ser-1145, MOD:00812|Ser-481/Ser-519/Ser-557/Ser-595/Ser-697/Ser-735/Ser-974/Ser-1052, MOD:00804." [PRO:DNx, Reactome:R-HSA-1467405, Reactome:R-HSA-1472876]
comment: Category=organism-modification.
synonym: "hNOTCH4/SigPep-/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "12xFucT-8xGlcS-6xFucS-NOTCH4(24-2003)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1467405, Reactome:R-HSA-1472876]
synonym: "UniProtKB:Q99466, 24-2003, Thr-40/Thr-248/Thr-290/Thr-331/Thr-369/Thr-489/Thr-705/Thr-781/Thr-820/Thr-944/Thr-982/Thr-1060, MOD:00813|Ser-79/Ser-210/Ser-451/Ser-603/Ser-743/Ser-1145, MOD:00812|Ser-481/Ser-519/Ser-557/Ser-595/Ser-697/Ser-735/Ser-974/Ser-1052, MOD:00804" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q99466-1, 24-2003, Thr-40/Thr-248/Thr-290/Thr-331/Thr-369/Thr-489/Thr-705/Thr-781/Thr-820/Thr-944/Thr-982/Thr-1060, MOD:00813|Ser-79/Ser-210/Ser-451/Ser-603/Ser-743/Ser-1145, MOD:00812|Ser-481/Ser-519/Ser-557/Ser-595/Ser-697/Ser-735/Ser-974/Ser-1052, MOD:00804" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1467405 "PR:000085921 located_in GO:0005789"
xref: Reactome:R-HSA-1472876 "PR:000085921 located_in GO:0000139"
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: has_part MOD:00812 ! O-fucosyl-L-serine
relationship: has_part MOD:00813 ! O-fucosyl-L-threonine
relationship: has_part MOD:00804 ! O-glucosyl-L-serine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens