[Term] id: PR:O75460 name: serine/threonine-protein kinase/endoribonuclease IRE1 (human) def: "A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75460] comment: Category=organism-gene. synonym: "hERN1" EXACT PRO-short-label [PRO:DNx] synonym: "endoplasmic reticulum-to-nucleus signaling 1 (human)" EXACT [UniProtKB:O75460] synonym: "hIRE1p" EXACT [UniProtKB:O75460] synonym: "inositol-requiring protein 1 (human)" EXACT [UniProtKB:O75460] synonym: "Ire1-alpha (human)" EXACT [UniProtKB:O75460] synonym: "IRE1a (human)" EXACT [UniProtKB:O75460] synonym: "ERN1" RELATED Gene-based [UniProtKB:O75460] synonym: "IRE1" RELATED Gene-based [UniProtKB:O75460] xref: UniProtKB:O75460 xref: DTO:03100142 intersection_of: PR:000007185 ! serine/threonine-protein kinase/endoribonuclease IRE1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: has_gene_template HGNC:3449 ! ERN1 (human) relationship: has_canonical_sequence UniProtKB:O75460 ! O75460-1