[Term] id: PR:P41279 name: mitogen-activated protein kinase kinase kinase 8 (human) def: "A mitogen-activated protein kinase kinase kinase 8 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-gene. synonym: "hMAP3K8" EXACT PRO-short-label [PRO:DNx] synonym: "cancer Osaka thyroid oncogene (human)" EXACT [UniProtKB:P41279] synonym: "proto-oncogene c-Cot (human)" EXACT [UniProtKB:P41279] synonym: "serine/threonine-protein kinase cot (human)" EXACT [UniProtKB:P41279] synonym: "TPL-2 (human)" EXACT [UniProtKB:P41279] synonym: "tumor progression locus 2 (human)" EXACT [UniProtKB:P41279] synonym: "COT" RELATED Gene-based [UniProtKB:P41279] synonym: "ESTF" RELATED Gene-based [UniProtKB:P41279] synonym: "MAP3K8" RELATED Gene-based [UniProtKB:P41279] xref: UniProtKB:P41279 xref: Reactome:R-HSA-389388 "PR:P41279 located_in GO:0005829" xref: DTO:03100290 intersection_of: PR:000010140 ! mitogen-activated protein kinase kinase kinase 8 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: has_gene_template HGNC:6860 ! MAP3K8 (human) relationship: has_canonical_sequence UniProtKB:P41279 ! P41279-1