[Term]
id: PR:Q7Z6Z7
name: E3 ubiquitin-protein ligase HUWE1 (human)
def: "An E3 ubiquitin-protein ligase HUWE1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q7Z6Z7]
comment: Category=organism-gene.
synonym: "hHUWE1" EXACT PRO-short-label [PRO:DNx]
synonym: "ARF-binding protein 1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "ARF-BP1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "HECT, UBA and WWE domain-containing protein 1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "HECT-type E3 ubiquitin transferase HUWE1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "HectH9 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "homologous to E6AP carboxyl terminus homologous protein 9 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "large structure of UREB1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "LASU1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "Mcl-1 ubiquitin ligase E3 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "Mule (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "upstream regulatory element-binding protein 1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "URE-B1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "URE-binding protein 1 (human)" EXACT [UniProtKB:Q7Z6Z7]
synonym: "HSPC272" RELATED Gene-based [UniProtKB:Q7Z6Z7]
synonym: "HUWE1" RELATED Gene-based [UniProtKB:Q7Z6Z7]
synonym: "KIAA0312" RELATED Gene-based [UniProtKB:Q7Z6Z7]
synonym: "KIAA1578" RELATED Gene-based [UniProtKB:Q7Z6Z7]
synonym: "UREB1" RELATED Gene-based [UniProtKB:Q7Z6Z7]
xref: UniProtKB:Q7Z6Z7
xref: Reactome:R-HSA-6801467 "PR:Q7Z6Z7 located_in GO:1904813"
xref: Reactome:R-HSA-6801481 "PR:Q7Z6Z7 located_in GO:0034774"
xref: Reactome:R-HSA-6806466 "PR:Q7Z6Z7 located_in GO:0005576"
xref: Reactome:R-HSA-975983 "PR:Q7Z6Z7 located_in GO:0005829"
intersection_of: PR:000008845 ! E3 ubiquitin-protein ligase HUWE1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_gene_template HGNC:30892 ! HUWE1 (human)
relationship: has_canonical_sequence UniProtKB:Q7Z6Z7 ! Q7Z6Z7-1