[Term]
id: PR:000001005
name: integrin alpha with A domain
def: "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage." [PIRSF:PIRSF002497]
comment: Category=family.
synonym: "integrin alpha with I domain" EXACT []
xref: PIRSF:PIRSF002497
is_a: PR:000025796 ! integrin alpha