[Term]
id: PR:000048295
name: dual specificity mitogen-activated protein kinase kinase 1, initiator methionine removed phosphorylated 4 (human)
def: "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 286 and 292 of the amino acid sequence represented by UniProtKB:Q02750. UniProtKB:Q02750, 2-393, Thr-286/Thr-292, MOD:00047." [PRO:DNx, Reactome:R-HSA-112374]
comment: Category=organism-modification.
synonym: "hMAP2K1/InitMet-/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000086365, Thr-286/Thr-292, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q02750, 2-393, Thr-286/Thr-292, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-112374 "PR:000048295 located_in GO:0005829"
is_a: PR:Q02750 ! dual specificity mitogen-activated protein kinase kinase 1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens