[Term]
id: PR:000049129
name: ribosomal protein S6 kinase alpha-3 phosphorylated 1 (human)
def: "A ribosomal protein S6 kinase alpha-3 (human) that has been post-translationally modified to include phosphoserine at positions 227, 369, 386, and 737, and phosphothreonine at position 365, and 577 of the amino acid sequence represented by UniProtKB:P51812. UniProtKB:P51812, Ser-227/Ser-369/Ser-386/Ser-737, MOD:00046|Thr-365/Thr-577, MOD:00047." [PRO:DAN, Reactome:R-HSA-444286]
comment: Category=organism-modification. Note: The modified sites indicated here (Ser-227/Ser-369/Ser-386/Ser-737/Thr-365/Thr-577) are referred to as Ser-222/Ser-364/Ser-381/Ser-733/Thr-360/Thr-574 in the literature using the rat Rps6ka1 sequence. [PRO:DAN, PMID:9430688]
synonym: "hRPS6KA3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51812, Ser-227/Ser-369/Ser-386/Ser-737, MOD:00046|Thr-365/Thr-577, MOD:00047" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-444286 "PR:000049129 located_in GO:0005654"
is_a: PR:P51812 ! ribosomal protein S6 kinase alpha-3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens