[Term]
id: PR:000064243
name: mast/stem cell growth factor receptor Kit sequence variant N822I, signal peptide removed phosphorylated 1 (human)
def: "A mast/stem cell growth factor receptor Kit (human) that has an Ile residue at the position equivalent to Asn-822 of the amino acid sequence represented by UniProtKB:P10721-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-568, Tyr-570, Tyr-703, Tyr-721, Tyr-730, Tyr-823, and Tyr-936. Example: UniProtKB:P10721-1, 26-976, Tyr-568/Tyr-570/Tyr-703/Tyr-721/Tyr-730/Tyr-823/Tyr-936, MOD:00048|Asn-822, CHEBI:30009." [PRO:DNx, Reactome:R-HSA-9669608]
comment: Category=organism-modification.
synonym: "hKIT/var:N822I/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10721, 26-976, Tyr-568/Tyr-570/Tyr-703/Tyr-721/Tyr-730/Tyr-823/Tyr-936, MOD:00048|Asn-822, CHEBI:30009" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10721-1, 26-976, Tyr-568/Tyr-570/Tyr-703/Tyr-721/Tyr-730/Tyr-823/Tyr-936, MOD:00048|Asn-822, CHEBI:30009" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "p7Y-KIT N822I" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9669608]
xref: Reactome:R-HSA-9669608 "PR:000064243 located_in GO:0005886"
is_a: PR:P10721 ! mast/stem cell growth factor receptor Kit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine