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Documentation
Protein Ontology report - fungal/metazoan cullin-1
PR:000000092 -
http://purl.obolibrary.org/obo/PR_000000092
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
/
PAF
PRO ID
PR:000000092
PRO name
fungal/metazoan cullin-1
Synonyms
PRO-Short-label
:
EXACT:
CUL1
Other
:
EXACT:
CUL-1
Definition
"A cullin that is a translation product of the human CUL1 gene or a 1:1 ortholog thereof in fungi or metazoa." [PRO:CNA]
PRO Category
gene
Parent
PR:000000013
cullin
PR:000036194
eukaryotic protein
Taxon
NCBITaxon:33154
Opisthokonta
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
7
Sequence
1
Organism-Sequence
2
Modification
2
Organism-Modification
4
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
gene
PR:000000092
fungal/metazoan cullin-1
CUL1
Yes
organism-gene
PR:O13790
cullin-1 (Schizosaccharomyces pombe 972h-)
Spom972h-CUL1
organism-gene
PR:O60999
cullin-1 (Dictyostelium discoideum)
Dicty-CUL1
organism-gene
PR:Q12018
cell division control protein 53 (yeast)
yCUL1
organism-gene
PR:Q13616
cullin-1 (human)
hCUL1
Yes
organism-sequence
PR:Q13616-1
cullin-1 isoform 1 (human)
hCUL1/iso:1
Yes
organism-modification
PR:000036454
cullin-1 isoform 1 neddylated 1 (human)
hCUL1/iso:1/Nedd:1
Yes
organism-modification
PR:000064861
cullin-1 neddylated 1 (human)
hCUL1/Nedd:1
organism-modification
PR:000071994
cullin-1 methylated 1 (human)
hCUL1/Me:1
organism-modification
PR:000075174
cullin-1 cysteinylated 1 (human)
hCUL1/Cyst:1
organism-gene
PR:Q17389
cullin-1 (worm)
CUL1 (worm)
organism-gene
PR:Q24311
cullin homolog 1 (fruit fly)
fly-CUL1
organism-gene
PR:Q9WTX6
cullin-1 (mouse)
mCUL1
organism-sequence
PR:Q9WTX6-1
cullin-1 isoform 1 (mouse)
mCUL1/iso:1
sequence
PR:000000267
fungal/metazoan cullin-1 isoform 1
CUL1/iso:1
organism-sequence
PR:Q13616-1
cullin-1 isoform 1 (human)
hCUL1/iso:1
Yes
organism-modification
PR:000036454
cullin-1 isoform 1 neddylated 1 (human)
hCUL1/iso:1/Nedd:1
Yes
organism-sequence
PR:Q9WTX6-1
cullin-1 isoform 1 (mouse)
mCUL1/iso:1
modification
PR:000000427
fungal/metazoan cullin-1 isoform 1 neddylated form
CUL1/iso:1/NeddLys+
modification
PR:000000542
fungal/metazoan cullin-1 isoform 1 neddylated 1
CUL1/iso:1/Nedd:1
organism-modification
PR:000036454
cullin-1 isoform 1 neddylated 1 (human)
hCUL1/iso:1/Nedd:1
Yes
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CUL1
forms found in complexes
CUL1
Component
Complexes
PR:Q13616
hCUL1
PR:000026771
SCF beta-TrCP complex (human)
PR:000026772
SCF(Skp2) complex (human)
PR:000037513
FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
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Functional Annotation (GO-centric view)
Switch to
PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0008285
negative regulation of cell population proliferation
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:8681378
GO:0031146
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
PR:000000092
CUL1
PANTHER:PTHR11932
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:10713156
;
PMID:10921923
GO:0051726
regulation of cell cycle
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:8681378
GO:0097193
intrinsic apoptotic signaling pathway
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:8681378
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515
protein binding
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
PR:Q13616-1
hCUL1/iso:1
PMID:12504026
;
PMID:15537541
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0019005
SCF ubiquitin ligase complex
PR:000000092
CUL1
PANTHER:PTHR11932
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:10713156
;
PMID:10921923
;
PMID:17098746
NOT
GO:0019005
SCF ubiquitin ligase complex
PR:Q13616-1
hCUL1/iso:1
PMID:10713156
;
PMID:10921923
;
PMID:12504026