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Protein Ontology report - transcription factor Sp1
PR:000000133 - http://purl.obolibrary.org/obo/PR_000000133
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000133   
  PRO nametranscription factor Sp1 
  Synonyms
PRO-Short-label: EXACT:SP1
Gene-based: RELATED:TSFP1
  Definition"A transcription factor Sp that is a translation product of the human SP1 gene or a 1:1 ortholog thereof. It comprises the exons that code for an N-terminal inhibitory domain, two serine/threonine stretches adjacent to activation domains and three zinc fingers." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000032 transcription factor Sp
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification14                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
gene


PR:000000133 transcription factor Sp1
SP1

organism-gene


PR:O89090 transcription factor Sp1 (mouse)
mSP1

organism-sequence


PR:O89090-1 transcription factor Sp1 isoform 1 (mouse)
mSP1/iso:1

organism-sequence


PR:O89090-2 transcription factor Sp1 isoform m2 (mouse)
mSP1/iso:m2

organism-gene


PR:P08047 transcription factor Sp1 (human)
hSP1

organism-sequence


PR:P08047-1 transcription factor Sp1 isoform 1 (human)
hSP1/iso:1
Yes
organism-modification


PR:000028672 transcription factor Sp1 isoform 1 acetylated 2 (human)
hSP1/iso:1/Ac:2

organism-modification


PR:000036496 transcription factor Sp1 isoform 1 acetylated 1 (human)
hSP1/iso:1/Ac:1
Yes
organism-modification


PR:000036497 transcription factor Sp1 isoform 1 cleaved 1 (human)
hSP1/iso:1/Clv:1
Yes
organism-modification


PR:000036498 transcription factor Sp1 isoform 1 O-glycosylated 1 (human)
hSP1/iso:1/OGlyco:1
Yes
organism-modification


PR:000036499 transcription factor Sp1 isoform 1 phosphorylated 1 (human)
hSP1/iso:1/Phos:1
Yes
organism-modification


PR:000036500 transcription factor Sp1 isoform 1 phosphorylated 2 (human)
hSP1/iso:1/Phos:2
Yes
organism-modification


PR:000036501 transcription factor Sp1 isoform 1 phosphorylated 3 (human)
hSP1/iso:1/Phos:3
Yes
organism-modification


PR:000036502 transcription factor Sp1 isoform 1 phosphorylated 4 (human)
hSP1/iso:1/Phos:4
Yes
organism-modification


PR:000036503 transcription factor Sp1 isoform 1 sumoylated 1 (human)
hSP1/iso:1/Sumo:1
Yes
organism-sequence


PR:P08047-2 transcription factor Sp1 isoform h2 (human)
hSP1/iso:h2

organism-sequence


PR:P08047-3 transcription factor Sp1 isoform h3 (human)
hSP1/iso:h3

organism-modification


PR:000045654 transcription factor Sp1 phosphorylated 1 (human)
hSP1/Phos:1

organism-modification


PR:000049324 transcription factor Sp1, initiator methionine removed form (human)
hSP1/InitMet-

organism-modification


PR:000069002 transcription factor Sp1 methylated 1 (human)
hSP1/Me:1

organism-modification


PR:000073305 transcription factor Sp1 deaminated 1 (human)
hSP1/Deam:1

organism-modification


PR:000080651 transcription factor Sp1 cysteinylated 1 (human)
hSP1/Cyst:1

organism-gene


PR:Q01714 transcription factor Sp1 (rat)
rSP1

organism-gene


PR:Q90WR9 transcription factor (chicken)
chick-SP1

sequence


PR:000000380 transcription factor Sp1 isoform 1
SP1/iso:1

organism-sequence


PR:O89090-1 transcription factor Sp1 isoform 1 (mouse)
mSP1/iso:1

organism-sequence


PR:P08047-1 transcription factor Sp1 isoform 1 (human)
hSP1/iso:1
Yes
organism-modification


PR:000028672 transcription factor Sp1 isoform 1 acetylated 2 (human)
hSP1/iso:1/Ac:2

organism-modification


PR:000036496 transcription factor Sp1 isoform 1 acetylated 1 (human)
hSP1/iso:1/Ac:1
Yes
organism-modification


PR:000036497 transcription factor Sp1 isoform 1 cleaved 1 (human)
hSP1/iso:1/Clv:1
Yes
organism-modification


PR:000036498 transcription factor Sp1 isoform 1 O-glycosylated 1 (human)
hSP1/iso:1/OGlyco:1
Yes
organism-modification


PR:000036499 transcription factor Sp1 isoform 1 phosphorylated 1 (human)
hSP1/iso:1/Phos:1
Yes
organism-modification


PR:000036500 transcription factor Sp1 isoform 1 phosphorylated 2 (human)
hSP1/iso:1/Phos:2
Yes
organism-modification


PR:000036501 transcription factor Sp1 isoform 1 phosphorylated 3 (human)
hSP1/iso:1/Phos:3
Yes
organism-modification


PR:000036502 transcription factor Sp1 isoform 1 phosphorylated 4 (human)
hSP1/iso:1/Phos:4
Yes
organism-modification


PR:000036503 transcription factor Sp1 isoform 1 sumoylated 1 (human)
hSP1/iso:1/Sumo:1
Yes
modification


PR:000000490 transcription factor Sp1 isoform 1 acetylated form
SP1/iso:1/AcRes+

modification


PR:000000596 transcription factor Sp1 isoform 1 acetylated 1
SP1/iso:1/Ac:1

organism-modification


PR:000036496 transcription factor Sp1 isoform 1 acetylated 1 (human)
hSP1/iso:1/Ac:1
Yes
modification


PR:000028671 transcription factor Sp1 isoform 1 acetylated 2
SP1/iso:1/Ac:2

organism-modification


PR:000028672 transcription factor Sp1 isoform 1 acetylated 2 (human)
hSP1/iso:1/Ac:2

modification


PR:000000492 transcription factor Sp1 isoform 1 glycosylated form
SP1/iso:1/GlycoRes+

modification


PR:000000598 transcription factor Sp1 isoform 1 O-glycosylated 1
SP1/iso:1/OGlyco:1

organism-modification


PR:000036498 transcription factor Sp1 isoform 1 O-glycosylated 1 (human)
hSP1/iso:1/OGlyco:1
Yes
modification


PR:000000493 transcription factor Sp1 isoform 1 phosphorylated form
SP1/iso:1/PhosRes+

modification


PR:000000599 transcription factor Sp1 isoform 1 phosphorylated 1
SP1/iso:1/Phos:1

organism-modification


PR:000036499 transcription factor Sp1 isoform 1 phosphorylated 1 (human)
hSP1/iso:1/Phos:1
Yes
modification


PR:000000600 transcription factor Sp1 isoform 1 phosphorylated 2
SP1/iso:1/Phos:2

organism-modification


PR:000036500 transcription factor Sp1 isoform 1 phosphorylated 2 (human)
hSP1/iso:1/Phos:2
Yes
modification


PR:000000601 transcription factor Sp1 isoform 1 phosphorylated 3
SP1/iso:1/Phos:3

organism-modification


PR:000036501 transcription factor Sp1 isoform 1 phosphorylated 3 (human)
hSP1/iso:1/Phos:3
Yes
modification


PR:000000602 transcription factor Sp1 isoform 1 phosphorylated 4
SP1/iso:1/Phos:4

organism-modification


PR:000036502 transcription factor Sp1 isoform 1 phosphorylated 4 (human)
hSP1/iso:1/Phos:4
Yes
modification


PR:000000494 transcription factor Sp1 isoform 1 sumoylated form
SP1/iso:1/SumoLys+

modification


PR:000000603 transcription factor Sp1 isoform 1 sumoylated 1
SP1/iso:1/Sumo:1

organism-modification


PR:000036503 transcription factor Sp1 isoform 1 sumoylated 1 (human)
hSP1/iso:1/Sumo:1
Yes
modification


PR:000000597 transcription factor Sp1 isoform 1 cleaved 1
SP1/iso:1/Clv:1

organism-modification


PR:000036497 transcription factor Sp1 isoform 1 cleaved 1 (human)
hSP1/iso:1/Clv:1
Yes
modification


PR:000025441 transcription factor Sp1 proteolytic cleavage product
SP1/ClvPrd

modification


PR:000000597 transcription factor Sp1 isoform 1 cleaved 1
SP1/iso:1/Clv:1

organism-modification


PR:000036497 transcription factor Sp1 isoform 1 cleaved 1 (human)
hSP1/iso:1/Clv:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036496 hSP1/iso:1/Ac:1 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:15647279
enablesGO:0003677 DNA binding PMID:15647279
located_inGO:0005634 nucleus PMID:15647279
PR:000036497 hSP1/iso:1/Clv:1
UniProtKB:P08047-1, 65-785		 enablesGO:0003700 DNA-binding transcription factor activity PMID:16407261
located_inGO:0005634 nucleus PMID:16407261
PR:000036498 hSP1/iso:1/OGlyco:1
UniProtKB:P08047-1, Ser-491, MOD:00805		 enablesGO:0003677 DNA binding PMID:11371615
increased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:11371615
located_inGO:0005634 nucleus PMID:11371615
PR:000036499 hSP1/iso:1/Phos:1 enablesGO:0003677 DNA binding PMID:2170018
located_inGO:0005634 nucleus PMID:2170018; PMID:9525578
PR:000036500 hSP1/iso:1/Phos:2
UniProtKB:P08047-1, Thr-579, MOD:00047		 enablesdecreased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:9153193
located_inGO:0005634 nucleus PMID:9153193
PR:000036501 hSP1/iso:1/Phos:3
UniProtKB:P08047-1, Ser-59, MOD:00046		 enablesincreased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:17049555; PMID:18239466
located_inGO:0005634 nucleus PMID:17049555; PMID:18239466
PR:000036502 hSP1/iso:1/Phos:4 acts_upstream_of_or_withinGO:0042770 signal transduction in response to DNA damage PMID:18171990
located_inGO:0005634 nucleus PMID:18171990
PR:000036503 hSP1/iso:1/Sumo:1
UniProtKB:P08047-1, Lys-16, MOD:01149		 enablesdecreased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:16407261
PR:P08047-1 hSP1/iso:1 located_inGO:0005634 nucleus PMID:2170018