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RACE-PRO
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Documentation
Protein Ontology report - activin receptor type-2A isoform 1
PR:000000208 -
http://purl.obolibrary.org/obo/PR_000000208
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000208
PRO name
activin receptor type-2A isoform 1
Synonyms
PRO-Short-label
:
EXACT:
ACVR2A/iso:1
Definition
"An activin receptor type-2A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P27038-1
or a 1:1 ortholog thereof." [
PMID:8395525
, PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000070
activin receptor type-2A
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
2
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
sequence
PR:000000208
activin receptor type-2A isoform 1
ACVR2A/iso:1
organism-sequence
PR:P27037-1
activin receptor type-2A isoform 1 (human)
hACVR2A/iso:1
organism-modification
PR:000036441
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human)
hACVR2A/iso:1/GlycoPhos:1
Yes
organism-sequence
PR:P27038-1
activin receptor type-2A isoform 1 (mouse)
mACVR2A/iso:1
Yes
organism-modification
PR:000036440
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse)
mACVR2A/iso:1/GlycoPhos:1
Yes
modification
PR:000000414
activin receptor type-2A isoform 1 glycosylated and phosphorylated form
ACVR2A/iso:1/GlycoPhos+
modification
PR:000000528
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1
ACVR2A/iso:1/GlycoPhos:1
organism-modification
PR:000036440
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse)
mACVR2A/iso:1/GlycoPhos:1
Yes
organism-modification
PR:000036441
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human)
hACVR2A/iso:1/GlycoPhos:1
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036440
mACVR2A/iso:1/GlycoPhos:1
acts_upstream_of_or_within
GO:0008584
male gonad development
PMID:7885474
GO:0009952
anterior/posterior pattern specification
PMID:10452853
;
PMID:16991118
enables
GO:0004675
transmembrane receptor protein serine/threonine kinase activity
PMID:8395525
GO:0016362
activin receptor activity, type II
PMID:8395525
GO:0019838
growth factor binding
PMID:11459935
;
PMID:12414726
GO:0042803
protein homodimerization activity
PMID:8612709
located_in
GO:0048179
activin receptor complex
PMID:8395525
PR:000036441
hACVR2A/iso:1/GlycoPhos:1
acts_upstream_of_or_within
GO:0007178
cell surface receptor protein serine/threonine kinase signaling pathway
PMID:1314589
enables
GO:0016362
activin receptor activity, type II
PMID:12665502
located_in
GO:0005886
plasma membrane
PMID:1314589
GO:0048179
activin receptor complex
PMID:8622651
PR:P27038-1
mACVR2A/iso:1
acts_upstream_of_or_within
GO:0007178
cell surface receptor protein serine/threonine kinase signaling pathway
PMID:8395525