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Protein Ontology report - activin receptor type-2B isoform ActR-IIB2
PR:000000209 -
http://purl.obolibrary.org/obo/PR_000000209
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000209
PRO name
activin receptor type-2B isoform ActR-IIB2
Synonyms
PRO-Short-label
:
EXACT:
ACVR2B/iso:ActR-IIB2
Other
:
EXACT:
activin receptor type-2B isoform 1 | ACVR2B isoform 1
Definition
"An activin receptor type-2B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P27040-2
or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
Comment
Note: This isoform lacks the intracellular segment rich in basic and acidic residues (known as splicing cassette II).
PRO Category
sequence
Parent
PR:000000071
activin receptor type-2B
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
3
Modification
2
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
sequence
PR:000000209
activin receptor type-2B isoform ActR-IIB2
ACVR2B/iso:ActR-IIB2
organism-sequence
PR:P27040-2
activin receptor type-2B isoform ActR-IIB2 (mouse)
mACVR2B/iso:ActR-IIB2
organism-modification
PR:000036442
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse)
mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
organism-sequence
PR:Q13705-1
activin receptor type-2B isoform ActR-IIB2 (human)
hACVR2B/iso:ActR-IIB2
Yes
organism-modification
PR:000036443
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human)
hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
organism-sequence
PR:Q90670-1
activin receptor type-2B isoform ActR-IIB2 (chicken)
chick-ACVR2B/iso:ActR-IIB2
modification
PR:000000415
activin receptor type-2B isoform ActR-IIB2 glycosylated and phosphorylated form
ACVR2B/iso:ActR-IIB2/GlycoPhos+
modification
PR:000000529
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1
ACVR2B/iso:ActR-IIB2/NGlycoPhos:1
organism-modification
PR:000036442
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse)
mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
organism-modification
PR:000036443
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human)
hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036442
mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
acts_upstream_of_or_within
GO:0007178
cell surface receptor protein serine/threonine kinase signaling pathway
PMID:8721982
GO:0009952
anterior/posterior pattern specification
PMID:10452853
;
PMID:16991118
GO:0032925
regulation of activin receptor signaling pathway
PMID:8721982
enables
GO:0004675
transmembrane receptor protein serine/threonine kinase activity
PMID:1326537
GO:0019838
growth factor binding
PMID:11459935
;
PMID:12414726
NOT
GO:0050431
transforming growth factor beta binding
PMID:1326537
PR:000036443
hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
enables
GO:0004675
transmembrane receptor protein serine/threonine kinase activity
PMID:8622651
GO:0005515
protein binding
PMID:11279102
;
PMID:9872992
GO:0016362
activin receptor activity, type II
PMID:8622651
located_in
GO:0005886
plasma membrane
PMID:8161782
GO:0048179
activin receptor complex
PMID:8622651
PR:Q13705-1
hACVR2B/iso:ActR-IIB2
acts_upstream_of_or_within
GO:0007178
cell surface receptor protein serine/threonine kinase signaling pathway
PMID:8161782
