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Protein Ontology report - activin/inhibin beta A chain
PR:000000216 - http://purl.obolibrary.org/obo/PR_000000216
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000216   
  PRO nameactivin/inhibin beta A chain 
  Synonyms
PRO-Short-label: EXACT:INHBA
Other: EXACT:activin beta-A chain | EDF | erythroid differentiation protein
  Definition"An activin/inhibin beta subunit that is a translation product of the human INHBA gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000072 activin/inhibin beta subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
gene


PR:000000216 activin/inhibin beta A chain
INHBA

organism-gene


PR:P08476 inhibin beta A chain (human)
hINHBA

organism-sequence


PR:P08476-1 inhibin beta A chain isoform 1 (human)
hINHBA/iso:1
Yes
organism-modification


PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human)
hINHBA/iso:1/Clv:1
Yes
organism-modification


PR:000054446 inhibin beta A chain O-glycosylated 1 (human)
hINHBA/OGlyco:1

organism-gene


PR:P18331 inhibin beta A chain (rat)
rINHBA

organism-gene


PR:P27092 inhibin beta A chain (chicken)
chick-INHBA

organism-gene


PR:Q04998 inhibin beta A chain (mouse)
mINHBA

organism-sequence


PR:Q04998-1 inhibin beta A chain isoform 1 (mouse)
mINHBA/iso:1

organism-modification


PR:000036539 activin/inhibin beta A chain isoform 1 cleaved 1 (mouse)
mINHBA/iso:1/Clv:1
Yes
sequence


PR:000000416 activin/inhibin beta A chain isoform 1
INHBA/iso:1

organism-sequence


PR:P08476-1 inhibin beta A chain isoform 1 (human)
hINHBA/iso:1
Yes
organism-modification


PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human)
hINHBA/iso:1/Clv:1
Yes
organism-sequence


PR:Q04998-1 inhibin beta A chain isoform 1 (mouse)
mINHBA/iso:1

organism-modification


PR:000036539 activin/inhibin beta A chain isoform 1 cleaved 1 (mouse)
mINHBA/iso:1/Clv:1
Yes
modification


PR:000021911 activin/inhibin beta A chain isoform 1, signal peptide removed form
INHBA/iso:1/SigPep-

modification


PR:000000637 activin/inhibin beta A chain isoform 1 cleaved 1
INHBA/iso:1/Clv:1

organism-modification


PR:000036539 activin/inhibin beta A chain isoform 1 cleaved 1 (mouse)
mINHBA/iso:1/Clv:1
Yes
organism-modification


PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human)
hINHBA/iso:1/Clv:1
Yes
modification


PR:000018295 activin/inhibin beta A chain proteolytic cleavage product
INHBA/ClvPrd

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036539 mINHBA/iso:1/Clv:1
UniProtKB:Q04998-1, 309-424		 enablescontributes_to GO:0005102 signaling receptor binding PMID:1646080; PMID:7577669
GO:0046983 protein dimerization activity PMID:2133547
PR:000036540 hINHBA/iso:1/Clv:1
UniProtKB:P08476-1, 311-426		 acts_upstream_of_or_withinGO:0007166 cell surface receptor signaling pathway PMID:12456957
GO:0007267 cell-cell signaling PMID:12456957
GO:0009605 response to external stimulus PMID:10320815
GO:0030154 cell differentiation PMID:12456957
GO:0032925 regulation of activin receptor signaling pathway PMID:9884026
enablescontributes_to GO:0005102 signaling receptor binding PMID:7890768
GO:0046983 protein dimerization activity PMID:1537316
located_inGO:0005576 extracellular region PMID:12213882; PMID:2575216
GO:0032991 protein-containing complex PMID:12960042
GO:0043509 activin A complex PMID:7890768
GO:0043512 inhibin A complex PMID:17456790; PMID:7890768
PR:P08476-1 hINHBA/iso:1 acts_upstream_of_or_withinGO:0001541 ovarian follicle development PMID:9166111
GO:0007165 signal transduction PMID:3267209
GO:0007267 cell-cell signaling PMID:12456957
GO:0007399 nervous system development PMID:10320815
GO:0030154 cell differentiation PMID:12456957
GO:0050789 regulation of biological process PMID:12419948; PMID:3122219