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Protein Ontology report - activin/inhibin beta E chain
PR:000000219 - http://purl.obolibrary.org/obo/PR_000000219
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000219   
  PRO nameactivin/inhibin beta E chain 
  Synonyms
PRO-Short-label: EXACT:INHBE
Other: EXACT:activin beta-E chain
  Definition"An activin/inhibin beta subunit that is a translation product of the human INHBE gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000072 activin/inhibin beta subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000000219

activin/inhibin beta E chain

INHBE


"An activin/inhibin beta subunit that is a translation product of the human INHBE gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O08717

inhibin beta E chain (mouse)

mINHBE


"An activin/inhibin beta E chain that is encoded in the genome of mouse." [OMA:O08717, PRO:DNx]


organism-sequence



PR:O08717-1

inhibin beta E chain isoform 1 (mouse)

mINHBE/iso:1


"An activin/inhibin beta E chain isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:O08717]


organism-modification



PR:000036542

activin/inhibin beta E chain isoform 1 cleaved 1 (mouse)

mINHBE/iso:1/Clv:1


"An activin/inhibin beta E chain isoform 1 cleaved 1 in mouse. UniProtKB:O08717-1, 237-350." [PMID:15863943, PRO:CNA]

Yes

organism-gene



PR:O88959

inhibin beta E chain (rat)

rINHBE


"An activin/inhibin beta E chain that is encoded in the genome of rat." [OMA:O88959, PRO:DNx]


organism-gene



PR:P58166

inhibin beta E chain (human)

hINHBE


"An activin/inhibin beta E chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P58166]


organism-sequence



PR:P58166-1

inhibin beta E chain isoform 1 (human)

hINHBE/iso:1


"An activin/inhibin beta E chain isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P58166]


organism-modification



PR:000056664

inhibin beta E chain O-glycosylated 1 (human)

hINHBE/OGlyco:1


"An inhibin beta E chain (human) that has been O-glycosylated at the residue equivalent to Thr-239 of the amino acid sequence represented by UniProtKB:P58166-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P58166-1, Thr-239, MOD:00005~GNO:G43417UB." [GlyGen:P58166-1, PMID:30459171, PRO:DNx]


sequence



PR:000000418

activin/inhibin beta E chain isoform 1

INHBE/iso:1


"An activin/inhibin beta E chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P58166-1 or a 1:1 ortholog thereof." [PMID:11134153, PRO:CNA, PRO:DAN]


organism-sequence



PR:O08717-1

inhibin beta E chain isoform 1 (mouse)

mINHBE/iso:1


"An activin/inhibin beta E chain isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:O08717]


organism-modification



PR:000036542

activin/inhibin beta E chain isoform 1 cleaved 1 (mouse)

mINHBE/iso:1/Clv:1


"An activin/inhibin beta E chain isoform 1 cleaved 1 in mouse. UniProtKB:O08717-1, 237-350." [PMID:15863943, PRO:CNA]

Yes

organism-sequence



PR:P58166-1

inhibin beta E chain isoform 1 (human)

hINHBE/iso:1


"An activin/inhibin beta E chain isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P58166]


modification



PR:000021913

activin/inhibin beta E chain isoform 1, signal peptide removed form

INHBE/iso:1/SigPep-


"An activin/inhibin beta E chain isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000639

activin/inhibin beta E chain isoform 1 cleaved 1

INHBE/iso:1/Clv:1


"An activin/inhibin beta E chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide, yielding the mature protein." [PMID:1286533, PRO:CNA]


organism-modification



PR:000036542

activin/inhibin beta E chain isoform 1 cleaved 1 (mouse)

mINHBE/iso:1/Clv:1


"An activin/inhibin beta E chain isoform 1 cleaved 1 in mouse. UniProtKB:O08717-1, 237-350." [PMID:15863943, PRO:CNA]

Yes

modification



PR:000021928

activin/inhibin beta E chain proteolytic cleavage product

INHBE/ClvPrd


"An activin/inhibin beta E chain that has been processed by proteolytic cleavage." [PRO:DAN]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036542 mINHBE/iso:1/Clv:1
UniProtKB:O08717-1, 237-350
acts_upstream_of_or_withinGO:0043065 positive regulation of apoptotic process PMID:15863943
enablesGO:0046983 protein dimerization activity PMID:15863943
located_inGO:0005576 extracellular region PMID:15863943
GO:0048180 activin complex PMID:15863943