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Protein Ontology report - Muellerian-inhibiting factor isoform 1

PR:000000220 - http://purl.obolibrary.org/obo/PR_000000220

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000000220

PRO name

Muellerian-inhibiting factor isoform 1

Synonyms

PRO-Short-label:	EXACT:	AMH/iso:1
Other:	RELATED:	AMH

Definition

"A Muellerian-inhibiting factor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27106-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

PRO Category

sequence

Parent

PR:000000073 Muellerian-inhibiting factor

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Sequence	1	Organism-Sequence	3
Modification	4	Organism-Modification	3

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

sequence

PR:000000220 Muellerian-inhibiting factor isoform 1

AMH/iso:1

organism-sequence

PR:P03971-1 Muellerian-inhibiting factor isoform 1 (human)

hAMH/iso:1

Yes

organism-modification

PR:000036605 Muellerian-inhibiting factor isoform 1 cleaved 1 (human)

hAMH/iso:1/Clv:1

Yes

organism-modification

PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)

hAMH/iso:1/ClvNGlyco:2

Yes

organism-sequence

PR:P27106-1 Muellerian-inhibiting factor isoform 1 (mouse)

mAmh/iso:1

organism-sequence

PR:P49000-1 Muellerian-inhibiting factor isoform 1 (rat)

rAMH/iso:1

organism-modification

PR:000036606 Muellerian-inhibiting factor isoform 1 cleaved 1 (rat)

rAMH/iso:1/Clv:1

Yes

modification

PR:000021919 Muellerian-inhibiting factor isoform 1, signal peptide removed form

AMH/iso:1/SigPep-

modification

PR:000001277 Muellerian-inhibiting factor isoform 1 cleaved 1

AMH/iso:1/Clv:1

modification

PR:000000419 Muellerian-inhibiting factor isoform 1 cleaved and glycosylated form

AMH/iso:1/ClvGlyco+

modification

PR:000000534 Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2

AMH/iso:1/ClvGlyco:2

organism-modification

PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)

hAMH/iso:1/ClvNGlyco:2

Yes

organism-modification

PR:000036605 Muellerian-inhibiting factor isoform 1 cleaved 1 (human)

hAMH/iso:1/Clv:1

Yes

organism-modification

PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)

hAMH/iso:1/ClvNGlyco:2

Yes

organism-modification

PR:000036606 Muellerian-inhibiting factor isoform 1 cleaved 1 (rat)

rAMH/iso:1/Clv:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036444 hAMH/iso:1/ClvNGlyco:2 UniProtKB:P03971-1, 26-450, 451-560, MOD:00160	acts_upstream_of_or_within	GO:0001880 Mullerian duct regression	PMID:14750901; PMID:3754790
		GO:0007267 cell-cell signaling	PMID:3754790
		GO:0007548 sex differentiation	PMID:12834017
	enables	GO:0005102 signaling receptor binding	PMID:14750901
		GO:0005179 hormone activity	PMID:14750901
		GO:0046983 protein dimerization activity	PMID:14673134
	located_in	GO:0005576 extracellular region	PMID:14750901; PMID:3754790
PR:000036605 hAMH/iso:1/Clv:1 UniProtKB:P03971-1, 451-560	enables	GO:0046983 protein dimerization activity	PMID:14673134
PR:000036606 rAMH/iso:1/Clv:1 UniProtKB:P49000-1, 446-553	located_in	GO:0005576 extracellular region	PMID:8755541
PR:P03971-1 hAMH/iso:1	acts_upstream_of_or_within	GO:0001880 Mullerian duct regression	PMID:14750901
PR:P03971-1 hAMH/iso:1	acts_upstream_of_or_within	GO:0007548 sex differentiation	PMID:12834017