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Protein Ontology report - Muellerian-inhibiting factor isoform 1
PR:000000220 - http://purl.obolibrary.org/obo/PR_000000220
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000220   
  PRO nameMuellerian-inhibiting factor isoform 1 
  Synonyms
PRO-Short-label: EXACT:AMH/iso:1
Other: RELATED:AMH
  Definition"A Muellerian-inhibiting factor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27106-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000073 Muellerian-inhibiting factor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 3                                        
         Modification4                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000000220

Muellerian-inhibiting factor isoform 1

AMH/iso:1


"A Muellerian-inhibiting factor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27106-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P03971-1

Muellerian-inhibiting factor isoform 1 (human)

hAMH/iso:1


"A Muellerian-inhibiting factor isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036605

Muellerian-inhibiting factor isoform 1 cleaved 1 (human)

hAMH/iso:1/Clv:1


"A Muellerian-inhibiting factor isoform 1 cleaved 1 in human. UniProtKB:P03971-1, 451-560." [PMID:14673134, PRO:CNA]

Yes

organism-modification



PR:000036444

Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)

hAMH/iso:1/ClvNGlyco:2


"A Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. The position(s) of glycosylation sites have not been experimentally determined. UniProtKB:P03971-1, 26-450, 451-560, MOD:00160." [PMID:12834017, PMID:14673134, PMID:14750901, PMID:3754790, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:P27106-1

Muellerian-inhibiting factor isoform 1 (mouse)

mAmh/iso:1


"A Muellerian-inhibiting factor isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P49000-1

Muellerian-inhibiting factor isoform 1 (rat)

rAMH/iso:1


"A Muellerian-inhibiting factor isoform 1 that is encoded in the genome of rat." [PRO:CNA]


organism-modification



PR:000036606

Muellerian-inhibiting factor isoform 1 cleaved 1 (rat)

rAMH/iso:1/Clv:1


"A Muellerian-inhibiting factor isoform 1 cleaved 1 in rat. UniProtKB:P49000-1, 446-553." [PMID:8755541, PRO:CNA]

Yes

modification



PR:000021919

Muellerian-inhibiting factor isoform 1, signal peptide removed form

AMH/iso:1/SigPep-


"A Muellerian-inhibiting factor isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000001277

Muellerian-inhibiting factor isoform 1 cleaved 1

AMH/iso:1/Clv:1


"A Muellerian-inhibiting factor isoform 1, signal peptide removed form that has had the propeptide removed by subsequent cleavage at the RxxR dibasic cleavage site. This form is the mature protein." [PMID:8755541, PRO:CNA]


modification



PR:000000419

Muellerian-inhibiting factor isoform 1 cleaved and glycosylated form

AMH/iso:1/ClvGlyco+


"A Muellerian-inhibiting factor isoform 1 cleaved 1 that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000000534

Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2

AMH/iso:1/ClvGlyco:2


"A Muellerian-inhibiting factor isoform 1 cleaved and glycosylated form that has been cleaved at the RxxR dibasic cleavage site rendering the propeptide and the mature protein non-covalently bound." [PMID:14673134]


organism-modification



PR:000036444

Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)

hAMH/iso:1/ClvNGlyco:2


"A Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. The position(s) of glycosylation sites have not been experimentally determined. UniProtKB:P03971-1, 26-450, 451-560, MOD:00160." [PMID:12834017, PMID:14673134, PMID:14750901, PMID:3754790, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036605

Muellerian-inhibiting factor isoform 1 cleaved 1 (human)

hAMH/iso:1/Clv:1


"A Muellerian-inhibiting factor isoform 1 cleaved 1 in human. UniProtKB:P03971-1, 451-560." [PMID:14673134, PRO:CNA]

Yes

organism-modification



PR:000036444

Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human)

hAMH/iso:1/ClvNGlyco:2


"A Muellerian-inhibiting factor isoform 1 cleaved and glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. The position(s) of glycosylation sites have not been experimentally determined. UniProtKB:P03971-1, 26-450, 451-560, MOD:00160." [PMID:12834017, PMID:14673134, PMID:14750901, PMID:3754790, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036606

Muellerian-inhibiting factor isoform 1 cleaved 1 (rat)

rAMH/iso:1/Clv:1


"A Muellerian-inhibiting factor isoform 1 cleaved 1 in rat. UniProtKB:P49000-1, 446-553." [PMID:8755541, PRO:CNA]

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0001880 Mullerian duct regressionPR:000036444 hAMH/iso:1/ClvNGlyco:2 PMID:14750901; PMID:3754790
PR:P03971-1 hAMH/iso:1 PMID:14750901
GO:0007267 cell-cell signalingPR:000036444 hAMH/iso:1/ClvNGlyco:2 PMID:3754790
GO:0007548 sex differentiationPR:000036444 hAMH/iso:1/ClvNGlyco:2 PMID:12834017
PR:P03971-1 hAMH/iso:1 PMID:12834017

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005102 signaling receptor bindingPR:000036444 hAMH/iso:1/ClvNGlyco:2 PMID:14750901
GO:0005179 hormone activityPR:000036444 hAMH/iso:1/ClvNGlyco:2 PMID:14750901
GO:0046983 protein dimerization activityPR:000036444 hAMH/iso:1/ClvNGlyco:2 PMID:14673134
PR:000036605 hAMH/iso:1/Clv:1 PMID:14673134

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005576 extracellular regionPR:000036444 hAMH/iso:1/ClvNGlyco:2 PMID:14750901; PMID:3754790
PR:000036606 rAMH/iso:1/Clv:1 PMID:8755541