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Protein Ontology report - decorin isoform A
PR:000000271 - http://purl.obolibrary.org/obo/PR_000000271
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000271   
  PRO namedecorin isoform A 
  Synonyms
PRO-Short-label: EXACT:DCN/iso:A
Other: EXACT:DCN isoform 1
  Definition"A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000094 decorin
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification5                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000000271

decorin isoform A

DCN/iso:A


"A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P07585-1

decorin isoform A (human)

hDCN/iso:A


"A decorin isoform A that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036456

decorin isoform A, mature form (human)

hDCN/iso:A/mature


"A decorin isoform A, mature form in human. UniProtKB:P07585-1, 31-359." [PMID:17651433, PMID:9988678, PRO:CNA]

Yes

organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036460

decorin isoform A cleaved 2 (human)

hDCN/iso:A/Clv:2


"A decorin isoform A cleaved 2 in human. UniProtKB:P07585-1, 31-170." [PMID:12621051, PMID:20947661, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000550

decorin isoform A cleaved 2

DCN/iso:A/Clv:2


"A decorin isoform A that has been cleaved after the Phe residue within the F[NS]GLN motif as a result of the catabolic processing of decorin. This form lacks most of the leucine-rich domains and is abundant in adult skin tissue." [PMID:12621051]


organism-modification



PR:000036460

decorin isoform A cleaved 2 (human)

hDCN/iso:A/Clv:2


"A decorin isoform A cleaved 2 in human. UniProtKB:P07585-1, 31-170." [PMID:12621051, PMID:20947661, PRO:CNA, PRO:DAN]

Yes

modification



PR:000021897

decorin isoform A, signal peptide removed form

DCN/iso:A/SigPep-


"A decorin isoform A that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000429

decorin isoform A cleaved and glycosylated form

DCN/iso:A/ClvGlyco+


"A decorin isoform A, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000000545

decorin isoform A cleaved and glycosylated 1

DCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated form that has been modified with O-linked glycosaminoglycan at the most N-terminal SG site and additional N-linked glycosylated Asn residues. Example: UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PRO:CNA, PRO:DAN]


organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000544

decorin isoform A, mature form

DCN/iso:A/mature


"A decorin isoform A, signal peptide removed form that has been processed by subsequent removal of the propeptide, rendering the mature decorin protein core." [PRO:CNA]


modification



PR:000000429

decorin isoform A cleaved and glycosylated form

DCN/iso:A/ClvGlyco+


"A decorin isoform A, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000000545

decorin isoform A cleaved and glycosylated 1

DCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated form that has been modified with O-linked glycosaminoglycan at the most N-terminal SG site and additional N-linked glycosylated Asn residues. Example: UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PRO:CNA, PRO:DAN]


organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036456

decorin isoform A, mature form (human)

hDCN/iso:A/mature


"A decorin isoform A, mature form in human. UniProtKB:P07585-1, 31-359." [PMID:17651433, PMID:9988678, PRO:CNA]

Yes

organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0030199 collagen fibril organizationPR:000036456 hDCN/iso:A/mature PMID:17651433
PR:000036457 hDCN/iso:A/ClvGlyco:1 PMID:17651433
PR:P07585-1 hDCN/iso:A PMID:17651433
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathwayPR:P07585-1 hDCN/iso:A PMID:11879191

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005154 epidermal growth factor receptor bindingPR:000036456 hDCN/iso:A/mature PMID:9988678
PR:000036457 hDCN/iso:A/ClvGlyco:1 PMID:9988678

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0031012 extracellular matrixPR:000036456 hDCN/iso:A/mature PMID:17651433
PR:000036457 hDCN/iso:A/ClvGlyco:1 PMID:17651433; PMID:9988678
PR:000036460 hDCN/iso:A/Clv:2 PMID:12621051