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Protein Ontology report - bone morphogenetic protein 7 isoform 1
PR:000000389 -
http://purl.obolibrary.org/obo/PR_000000389
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000389
PRO name
bone morphogenetic protein 7 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
BMP7/iso:1
Definition
"A bone morphogenetic protein 7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P18075-1
or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000168
bone morphogenetic protein 7
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
5
Organism-Modification
4
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
sequence
PR:000000389
bone morphogenetic protein 7 isoform 1
BMP7/iso:1
"A bone morphogenetic protein 7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18075-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
organism-sequence
PR:P18075-1
bone morphogenetic protein 7 isoform 1 (human)
hBMP7/iso:1
"A bone morphogenetic protein 7 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification
PR:000036517
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)
hBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]
Yes
organism-modification
PR:000036519
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)
hBMP7/iso:1/mature/NGlyco:2
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]
Yes
organism-sequence
PR:P23359-1
bone morphogenetic protein 7 isoform 1 (mouse)
mBMP7/iso:1
"A bone morphogenetic protein 7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
Yes
organism-modification
PR:000036516
bone morphogenetic protein 7 isoform 1, mature form (mouse)
mBMP7/iso:1/mature
"A bone morphogenetic protein 7 isoform 1, mature form in mouse. UniProtKB:P23359-1, 292-430." [PMID:12741987, PRO:CNA]
Yes
organism-modification
PR:000036518
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)
mBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]
Yes
modification
PR:000000612
bone morphogenetic protein 7 isoform 1, mature form
BMP7/iso:1/mature
"A bone morphogenetic protein 7 isoform 1 that has had the signal peptide and propeptide removed. Example: UniProtKB:P23359-1, 292-430." [PRO:CNA, PRO:DAN]
modification
PR:000000505
bone morphogenetic protein 7 isoform 1, mature glycosylated form
BMP7/iso:1/ClvGlyco+
"A bone morphogenetic protein 7 isoform 1, mature form that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]
modification
PR:000000613
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1
BMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that is N-glycosylated at the N{P}[ST]{P} motif. This form is a disulfide linked homodimer. Example: UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]
organism-modification
PR:000036517
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)
hBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]
Yes
organism-modification
PR:000036518
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)
mBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]
Yes
modification
PR:000000614
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2
BMP7/iso:1/mature/NGlyco:2
"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that has the propeptide still bound to the mature protein. This form is N-glycosylated at the most C-terminal N{P}[ST]{P} motif and is a homodimer. Example: UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982]
organism-modification
PR:000036519
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)
hBMP7/iso:1/mature/NGlyco:2
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]
Yes
organism-modification
PR:000036516
bone morphogenetic protein 7 isoform 1, mature form (mouse)
mBMP7/iso:1/mature
"A bone morphogenetic protein 7 isoform 1, mature form in mouse. UniProtKB:P23359-1, 292-430." [PMID:12741987, PRO:CNA]
Yes
organism-modification
PR:000036518
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)
mBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]
Yes
modification
PR:000021902
bone morphogenetic protein 7 isoform 1, signal peptide removed form
BMP7/iso:1/SigPep-
"A bone morphogenetic protein 7 isoform 1 that has had the signal peptide removed." [PRO:DNx]
modification
PR:000000612
bone morphogenetic protein 7 isoform 1, mature form
BMP7/iso:1/mature
"A bone morphogenetic protein 7 isoform 1 that has had the signal peptide and propeptide removed. Example: UniProtKB:P23359-1, 292-430." [PRO:CNA, PRO:DAN]
modification
PR:000000505
bone morphogenetic protein 7 isoform 1, mature glycosylated form
BMP7/iso:1/ClvGlyco+
"A bone morphogenetic protein 7 isoform 1, mature form that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]
modification
PR:000000613
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1
BMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that is N-glycosylated at the N{P}[ST]{P} motif. This form is a disulfide linked homodimer. Example: UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]
organism-modification
PR:000036517
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)
hBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]
Yes
organism-modification
PR:000036518
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)
mBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]
Yes
modification
PR:000000614
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2
BMP7/iso:1/mature/NGlyco:2
"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that has the propeptide still bound to the mature protein. This form is N-glycosylated at the most C-terminal N{P}[ST]{P} motif and is a homodimer. Example: UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982]
organism-modification
PR:000036519
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)
hBMP7/iso:1/mature/NGlyco:2
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]
Yes
organism-modification
PR:000036516
bone morphogenetic protein 7 isoform 1, mature form (mouse)
mBMP7/iso:1/mature
"A bone morphogenetic protein 7 isoform 1, mature form in mouse. UniProtKB:P23359-1, 292-430." [PMID:12741987, PRO:CNA]
Yes
organism-modification
PR:000036518
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)
mBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036516
mBMP7/iso:1/mature
UniProtKB:P23359-1, 292-430
acts_upstream_of_or_within
GO:0007411
axon guidance
PMID:12741987
enables
GO:0005515
protein binding
PMID:12741987
located_in
GO:0005615
extracellular space
PMID:12741987
PR:000036517
hBMP7/iso:1/mature/NGlyco:1
UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160
enables
GO:0005102
signaling receptor binding
PMID:9872992
GO:0042803
protein homodimerization activity
PMID:15929982
;
PMID:8570652
located_in
GO:0005615
extracellular space
PMID:15047707
;
PMID:15929982
PR:000036518
mBMP7/iso:1/mature/NGlyco:1
UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160
acts_upstream_of_or_within
GO:0030509
BMP signaling pathway
PMID:14623234
PR:000036519
hBMP7/iso:1/mature/NGlyco:2
UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160
enables
NOT
GO:0005102
signaling receptor binding
PMID:15929982
located_in
GO:0005615
extracellular space
PMID:15929982
PR:P18075-1
hBMP7/iso:1
acts_upstream_of_or_within
GO:0001501
skeletal system development
PMID:2357959
enables
GO:0005515
protein binding
PMID:12805376
located_in
GO:0005794
Golgi apparatus
PMID:12805376
PR:P23359-1
mBMP7/iso:1
acts_upstream_of_or_within
GO:0030509
BMP signaling pathway
PMID:14623234
