back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - TGF-beta 1 sequence variant T81H (human)
PR:000000399 - http://purl.obolibrary.org/obo/PR_000000399
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000000399   
  PRO nameTGF-beta 1 sequence variant T81H (human) 
  Synonyms
PRO-Short-label: EXACT:hTGFB1/var:T81H
PRO-proteoform-std: EXACT:UniProtKB:P01137, Tyr-81, CHEBI:29979
Other: EXACT:TGF-beta 1 sequence variant 2 (human)
  Definition"A transforming growth factor beta-1 (human) that has a His residue at the position equivalent to Tyr-81 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Tyr-81, CHEBI:29979." [PMID:11062463, PMID:12493741, PRO:CNA, PRO:DAN] 
  PRO Categoryorganism-sequence 
  ParentPR:P01137 transforming growth factor beta-1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
UniProtKB_VAR:VAR_017607
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-sequence


PR:000000399
TGF-beta 1 sequence variant T81H (human)
hTGFB1/var:T81H
"A transforming growth factor beta-1 (human) that has a His residue at the position equivalent to Tyr-81 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Tyr-81, CHEBI:29979." [PMID:11062463, PMID:12493741, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000021903
TGF-beta 1 sequence variant T81H, signal peptide removed form (human)
hTGFB1/var:T81H/SigPep-
"A TGF-beta 1 sequence variant T81H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Tyr-81, CHEBI:29979." [PRO:DAN]

organism-modification


PR:000000619
TGF-beta 1 sequence variant T81H cleaved 1 (human)
hTGFB1/var:T81H/Clv:1
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000000620
TGF-beta 1 sequence variant T81H cleaved 2 (human)
hTGFB1/var:T81H/Clv:2
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
Yes
Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000000399 hTGFB1/var:T81H PMID:11062463

Disease Associated GO Term
Protein Forms & Complexes
Evidence
DO:4997 Camurati-Engelmann diseasePR:000000399 hTGFB1/var:T81H PMID:12493741

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:000000620 hTGFB1/var:T81H/Clv:2 PMID:12493741
SO:0001558 polypeptide_localization_variantPR:000000399 hTGFB1/var:T81H PMID:11062463; PMID:12493741
PR:000000619 hTGFB1/var:T81H/Clv:1 PMID:12493741