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Protein Ontology report - activin receptor type-2A isoform 1 glycosylated and phosphorylated 1
PR:000000528 -
http://purl.obolibrary.org/obo/PR_000000528
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000528
PRO name
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
ACVR2A/iso:1/GlycoPhos:1
Definition
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated form in which the phosphorylation occurs at Ser/Thr residues. This constitutes the active receptor subunit." [
PMID:8395525
]
PRO Category
modification
Parent
PR:000000414
activin receptor type-2A isoform 1 glycosylated and phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000000528
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1
ACVR2A/iso:1/GlycoPhos:1
organism-modification
PR:000036440
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse)
mACVR2A/iso:1/GlycoPhos:1
Yes
organism-modification
PR:000036441
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human)
hACVR2A/iso:1/GlycoPhos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036440
mACVR2A/iso:1/GlycoPhos:1
acts_upstream_of_or_within
GO:0008584
male gonad development
PMID:7885474
GO:0009952
anterior/posterior pattern specification
PMID:10452853
;
PMID:16991118
enables
GO:0004675
transmembrane receptor protein serine/threonine kinase activity
PMID:8395525
GO:0016362
activin receptor activity, type II
PMID:8395525
GO:0019838
growth factor binding
PMID:11459935
;
PMID:12414726
GO:0042803
protein homodimerization activity
PMID:8612709
located_in
GO:0048179
activin receptor complex
PMID:8395525
PR:000036441
hACVR2A/iso:1/GlycoPhos:1
acts_upstream_of_or_within
GO:0007178
cell surface receptor protein serine/threonine kinase signaling pathway
PMID:1314589
enables
GO:0016362
activin receptor activity, type II
PMID:12665502
located_in
GO:0005886
plasma membrane
PMID:1314589
GO:0048179
activin receptor complex
PMID:8622651
