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Protein Ontology report - c-myc protein isoform 1 phosphorylated 1
PR:000000537 -
http://purl.obolibrary.org/obo/PR_000000537
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000537
PRO name
c-myc protein isoform 1 phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
MYC/iso:1/Phos:1
Definition
"A c-myc protein isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue within the L[LY]PTLTPPLS sequence of the Myc box I within the amino-terminal regulatory domain by ERK through activation of Raf signaling pathway. Example:
UniProtKB:P01106-1
, Ser-62,
MOD:00046
." [
PMID:11018017
]
PRO Category
modification
Parent
PR:000000422
c-myc protein isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000000537
c-myc protein isoform 1 phosphorylated 1
MYC/iso:1/Phos:1
"A c-myc protein isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue within the L[LY]PTLTPPLS sequence of the Myc box I within the amino-terminal regulatory domain by ERK through activation of Raf signaling pathway. Example: UniProtKB:P01106-1, Ser-62, MOD:00046." [PMID:11018017]
organism-modification
PR:000026052
c-myc protein isoform 1 phosphorylated 1 (mouse)
mMYC/iso:1/Phos:1
"A c-myc protein isoform 1 phosphorylated 1 in mouse. UniProtKB:P01108-1, Ser-62, MOD:00046." [PMID:15048125]
Yes
organism-modification
PR:000036448
c-myc protein isoform 1 phosphorylated 1 (human)
hMYC/iso:1/Phos:1
"A c-myc protein isoform 1 phosphorylated 1 in human. UniProtKB:P01106-1, Ser-62, MOD:00046." [PMID:19131971, PRO:CNA]
Yes
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Functional Annotation (GO-centric view)
Switch to
PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006357
regulation of transcription by RNA polymerase II
PR:000026052
mMYC/iso:1/Phos:1
PMID:11018017
GO:0006879
intracellular iron ion homeostasis
PR:000026052
mMYC/iso:1/Phos:1
PMID:11018017
GO:0008283
cell population proliferation
PR:000026052
mMYC/iso:1/Phos:1
PMID:11018017
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
PR:000026052
mMYC/iso:1/Phos:1
PMID:11018017
GO:0005515
protein binding
PR:000036448
hMYC/iso:1/Phos:1
PMID:19131971
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634
nucleus
PR:000026052
mMYC/iso:1/Phos:1
PMID:11018017
GO:0005667
transcription factor complex
PR:000026052
mMYC/iso:1/Phos:1
PMID:11018017
