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Protein Ontology report - c-myc protein isoform 1 phosphorylated 1
PR:000000537 - http://purl.obolibrary.org/obo/PR_000000537
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000537   
  PRO namec-myc protein isoform 1 phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:MYC/iso:1/Phos:1
  Definition"A c-myc protein isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue within the L[LY]PTLTPPLS sequence of the Myc box I within the amino-terminal regulatory domain by ERK through activation of Raf signaling pathway. Example: UniProtKB:P01106-1, Ser-62, MOD:00046." [PMID:11018017] 
  PRO Categorymodification 
  ParentPR:000000422 c-myc protein isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
modification


PR:000000537
c-myc protein isoform 1 phosphorylated 1
MYC/iso:1/Phos:1
"A c-myc protein isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue within the L[LY]PTLTPPLS sequence of the Myc box I within the amino-terminal regulatory domain by ERK through activation of Raf signaling pathway. Example: UniProtKB:P01106-1, Ser-62, MOD:00046." [PMID:11018017]

organism-modification


PR:000026052
c-myc protein isoform 1 phosphorylated 1 (mouse)
mMYC/iso:1/Phos:1
"A c-myc protein isoform 1 phosphorylated 1 in mouse. UniProtKB:P01108-1, Ser-62, MOD:00046." [PMID:15048125]
Yes
organism-modification


PR:000036448
c-myc protein isoform 1 phosphorylated 1 (human)
hMYC/iso:1/Phos:1
"A c-myc protein isoform 1 phosphorylated 1 in human. UniProtKB:P01106-1, Ser-62, MOD:00046." [PMID:19131971, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026052 mMYC/iso:1/Phos:1
UniProtKB:P01108-1, Ser-62, MOD:00046		 acts_upstream_of_or_withinGO:0006357 regulation of transcription by RNA polymerase II PMID:11018017
GO:0006879 intracellular iron ion homeostasis PMID:11018017
GO:0008283 cell population proliferation PMID:11018017
enablesGO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:11018017
located_inGO:0005634 nucleus PMID:11018017
GO:0005667 transcription factor complex PMID:11018017
PR:000036448 hMYC/iso:1/Phos:1
UniProtKB:P01106-1, Ser-62, MOD:00046		 enablesGO:0005515 protein binding with PR:O15169-1 PMID:19131971