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Protein Ontology report - fungal/metazoan cullin-1 isoform 1 neddylated 1
PR:000000542 -
http://purl.obolibrary.org/obo/PR_000000542
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000542
PRO name
fungal/metazoan cullin-1 isoform 1 neddylated 1
Synonyms
PRO-Short-label
:
EXACT:
CUL1/iso:1/Nedd:1
Definition
"A fungal/metazoan cullin-1 isoform 1 neddylated form that has been neddylated in the conserved Lys residue within the IVR[ILV]MKxR[RK] motif. Example:
UniProtKB:Q13616-1
, Lys-720,
MOD:01150
." [
PMID:10713156
]
PRO Category
modification
Parent
PR:000000427
fungal/metazoan cullin-1 isoform 1 neddylated form
Taxon
NCBITaxon:33154
Opisthokonta
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000000542
fungal/metazoan cullin-1 isoform 1 neddylated 1
CUL1/iso:1/Nedd:1
"A fungal/metazoan cullin-1 isoform 1 neddylated form that has been neddylated in the conserved Lys residue within the IVR[ILV]MKxR[RK] motif. Example: UniProtKB:Q13616-1, Lys-720, MOD:01150." [PMID:10713156]
organism-modification
PR:000036454
cullin-1 isoform 1 neddylated 1 (human)
hCUL1/iso:1/Nedd:1
"A fungal/metazoan cullin-1 isoform 1 neddylated 1 in human. UniProtKB:Q13616-1, Lys-720, MOD:01150." [PMID:10713156, PMID:10921923, PMID:17098746, PMID:8681378, PRO:CNA]
Yes
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0008285
negative regulation of cell population proliferation
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:8681378
GO:0031146
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:10713156
;
PMID:10921923
GO:0051726
regulation of cell cycle
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:8681378
GO:0097193
intrinsic apoptotic signaling pathway
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:8681378
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0019005
SCF ubiquitin ligase complex
PR:000036454
hCUL1/iso:1/Nedd:1
PMID:10713156
;
PMID:10921923
;
PMID:17098746