back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - tumor necrosis factor isoform 1 cleaved 1
PR:000000604 - http://purl.obolibrary.org/obo/PR_000000604
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000604   
  PRO nametumor necrosis factor isoform 1 cleaved 1 
  Synonyms
PRO-Short-label: EXACT:TNF/iso:1/Clv:1
Other: EXACT:tumor necrosis factor soluble form
  Definition"A tumor necrosis factor isoform 1 that is the soluble C-terminal portion after processing by TNF alpha converting enzyme ADAM17." [PMID:12135369
  PRO Categorymodification 
  ParentPR:000000381 tumor necrosis factor isoform 1
PR:000018285 tumor necrosis factor proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?
modification



PR:000000604 tumor necrosis factor isoform 1 cleaved 1

TNF/iso:1/Clv:1


organism-modification



PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human)

hTNF/iso:1/Clv:1

Yes

organism-modification



PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse)

mTNF/iso:1/Clv:1

Yes

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036504 hTNF/iso:1/Clv:1
UniProtKB:P01375-1, 77-233
acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:3856324
enablesGO:0005164 tumor necrosis factor receptor binding with PR:P19438 CD120a (human) PMID:14512626
GO:0042802 identical protein binding PMID:14512626
PR:000036505 mTNF/iso:1/Clv:1
UniProtKB:P06804-1, 80-235
acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PMID:9305915
located_inGO:0005615 extracellular space PMID:10089307