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Protein Ontology report - tumor necrosis factor isoform 1 cleaved 1
PR:000000604 - http://purl.obolibrary.org/obo/PR_000000604
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000604   
  PRO nametumor necrosis factor isoform 1 cleaved 1 
  Synonyms
PRO-Short-label: EXACT:TNF/iso:1/Clv:1
Other: EXACT:tumor necrosis factor soluble form
  Definition"A tumor necrosis factor isoform 1 that is the soluble C-terminal portion after processing by TNF alpha converting enzyme ADAM17." [PMID:12135369] 
  PRO Categorymodification 
  ParentPR:000000381 tumor necrosis factor isoform 1
PR:000018285 tumor necrosis factor proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
modification


PR:000000604
tumor necrosis factor isoform 1 cleaved 1
TNF/iso:1/Clv:1
"A tumor necrosis factor isoform 1 that is the soluble C-terminal portion after processing by TNF alpha converting enzyme ADAM17." [PMID:12135369]

organism-modification


PR:000036504
tumor necrosis factor isoform 1 cleaved 1 (human)
hTNF/iso:1/Clv:1
"A tumor necrosis factor isoform 1 cleaved 1 in human. UniProtKB:P01375-1, 77-233." [PMID:14512626, PMID:3856324, PRO:CNA]
Yes
organism-modification


PR:000036505
tumor necrosis factor isoform 1 cleaved 1 (mouse)
mTNF/iso:1/Clv:1
"A tumor necrosis factor isoform 1 cleaved 1 in mouse. UniProtKB:P06804-1, 80-235." [PMID:10089307, PMID:9305915, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036504 hTNF/iso:1/Clv:1
UniProtKB:P01375-1, 77-233		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:3856324
enablesGO:0005164 tumor necrosis factor receptor binding with PR:P19438 CD120a (human) PMID:14512626
GO:0042802 identical protein binding PMID:14512626
PR:000036505 mTNF/iso:1/Clv:1
UniProtKB:P06804-1, 80-235		 acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PMID:9305915
located_inGO:0005615 extracellular space PMID:10089307