back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - TGF-beta 1 sequence variant H222D cleaved 2 (human)
PR:000000624 - http://purl.obolibrary.org/obo/PR_000000624
 
    Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000000624   
  PRO nameTGF-beta 1 sequence variant H222D cleaved 2 (human) 
  Synonyms
PRO-Short-label: EXACT:hTGFB1/var:H222D/Clv:2
PRO-proteoform-std: EXACT:UniProtKB:P01137, 30-278, His-222, CHEBI:29958
Other: EXACT:TGF-beta 1 sequence variant 5 cleaved 2 (human)
  Definition"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, His-222, CHEBI:29958." [PMID:11278244, PRO:CNA, PRO:DAN] 
  PRO Categoryorganism-modification 
  ParentPR:000018292 TGF-beta 1 proteolytic cleavage product
PR:000021905 TGF-beta 1 sequence variant H222D, signal peptide removed form (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000624 hTGFB1/var:H222D/Clv:2
UniProtKB:P01137, 30-278, His-222, CHEBI:29958
located_inSO:0001561 polypeptide_partial_loss_of_function PMID:11278244
SO:0001601 conformational_change_variant PMID:11278244