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Protein Ontology report - TGF-beta 1 sequence variant C225R cleaved 2 (human)
PR:000000626 -
http://purl.obolibrary.org/obo/PR_000000626
Annotations
Ontology Information
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PAF
/
GPI
PRO ID
PR:000000626
PRO name
TGF-beta 1 sequence variant C225R cleaved 2 (human)
Synonyms
PRO-Short-label
:
EXACT:
hTGFB1/var:C225R/Clv:2
PRO-proteoform-std
:
EXACT:
UniProtKB:P01137
, 30-278, Cys-225,
CHEBI:29952
Other
:
EXACT:
TGF-beta 1 sequence variant 6 cleaved 2 (human)
Definition
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP).
UniProtKB:P01137
, 30-278, Cys-225,
CHEBI:29952
." [
PMID:11278244
, PRO:CNA, PRO:DAN]
PRO Category
organism-modification
Parent
PR:000018292
TGF-beta 1 proteolytic cleavage product
PR:000021906
TGF-beta 1 sequence variant C225R, signal peptide removed form (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000000626
hTGFB1/var:C225R/Clv:2
UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952
located_in
SO:0001561
polypeptide_partial_loss_of_function
PMID:11278244